6-Methyl-1H-benzimidazol-1-ol

Base Information

Chemical Name:6-Methyl-1H-benzimidazol-1-ol
CAS No.:62376-78-7
Molecular Formula:C8H8N2O
Molecular Weight:148.16200
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60490504
Wikidata:Q82334303
Mol file:62376-78-7.mol

Synonyms:6-Methyl-1H-benzimidazol-1-ol;62376-78-7;SCHEMBL11159254;DTXSID60490504

Suppliers and Price of 6-Methyl-1H-benzimidazol-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-Methyl-1H-benzimidazol-1-ol

Chemical Property:

Melting Point:176-178 °C(Solv: ethanol (64-17-5))
Boiling Point:348.6±35.0 °C(Predicted)
PKA:-6.48±0.14(Predicted)
PSA：38.05000
Density:1.27±0.1 g/cm3(Predicted)
LogP:1.58200
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:148.063662883
Heavy Atom Count:11
Complexity:151

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N=CN2O

Technology Process of 6-Methyl-1H-benzimidazol-1-ol

There total 10 articles about 6-Methyl-1H-benzimidazol-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1-Hydroxy-6-methyl-3H-benzoimidazol-1-ium; chloride

: 62376-78-7
5-methyl-benzimidazole 3-oxide

Guidance literature:: With ammonium hydroxide;

Reference yield:

: 71894-91-2
N-(4-methyl-2-nitrophenyl)formamide

: 62376-78-7
5-methyl-benzimidazole 3-oxide

Guidance literature:: With sodium tetrahydroborate; palladium on activated charcoal; In pyridine; at 35 - 40 ℃; for 0.25h;

Reference yield:

: 89-62-3
4-methyl-2-nitroaniline

: 62376-78-7
5-methyl-benzimidazole 3-oxide

Guidance literature:: Multi-step reaction with 6 steps

1: 75 percent / cc. sulphuric acid, ZnCl₂ / acetic acid

2: 67 percent / aq. sulphuric acid / acetic acid / 2.5 h / 100 °C

3: 83 percent / HCl / Heating

4: 46 percent / sodium ethoxide / ethanol; dimethylformamide / 2 h

5: 85 percent / cc. HCl / 4 h

6: 72 percent / aq.NH₃

With hydrogenchloride; ammonium hydroxide; sulfuric acid; sodium ethanolate; zinc(II) chloride; In ethanol; acetic acid; N,N-dimethyl-formamide;