5-(Bromoacetyl)-2-chlorobenzoic acid

Base Information

Chemical Name:5-(Bromoacetyl)-2-chlorobenzoic acid
CAS No.:62423-74-9
Molecular Formula:C9H6BrClO3
Molecular Weight:277.49900
Hs Code.:
DSSTox Substance ID:DTXSID10593776
Wikidata:Q82488322

Synonyms:62423-74-9;5-(Bromoacetyl)-2-chlorobenzoic acid;SCHEMBL18398130;DTXSID10593776

Suppliers and Price of 5-(Bromoacetyl)-2-chlorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 5-(Bromoacetyl)-2-chlorobenzoic acid

Chemical Property:

Boiling Point:424.1±35.0 °C(Predicted)
PSA：54.37000
Density:1.749±0.06 g/cm3(Predicted)
LogP:2.61580
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:275.91888
Heavy Atom Count:14
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(=O)CBr)C(=O)O)Cl

Technology Process of 5-(Bromoacetyl)-2-chlorobenzoic acid

There total 2 articles about 5-(Bromoacetyl)-2-chlorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl 5-acetyl-2-chlorobenzoate

: 62423-74-9
5-(2-bromoacetyl)-2-chlorobenzoic acid

Guidance literature:: With copper(ll) bromide; In chloroform; ethyl acetate; at 80 ℃; for 20h; Inert atmosphere;

Reference yield:

: 503555-23-5
tert-butyl 5-bromo-2-chloro-benzoate

: 62423-74-9
5-(2-bromoacetyl)-2-chlorobenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: diisopropylamine; 1,3-bis-(diphenylphosphino)propane; 1-butyl-3-methylimidazolium Tetrafluoroborate; palladium diacetate / dimethyl sulfoxide / 20 h / 110 °C / Inert atmosphere

2: copper(ll) bromide / ethyl acetate; chloroform / 20 h / 80 °C / Inert atmosphere

With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; diisopropylamine; 1-butyl-3-methylimidazolium Tetrafluoroborate; copper(ll) bromide; In chloroform; dimethyl sulfoxide; ethyl acetate;