2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole
CAS No.:62507-52-2
Molecular Formula:C15H11N3O3
Molecular Weight:281.271
Hs Code.:
European Community (EC) Number:636-374-2
DSSTox Substance ID:DTXSID40356912
Wikidata:Q82136551

Synonyms:2-(4-methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole;62507-52-2;2-(4-Nitrophenyl)-5-(p-tolyl)-1,3,4-oxadiazole;DTXSID40356912;2-(4-NITROPHENYL)-5-(4-TOLYL)-1,3,4-OXADIAZOLE;STK275866;AKOS000733237;CCG-311280;CS-0358757

Suppliers and Price of 2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:281.08004122
Heavy Atom Count:21
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NN=C(O2)C3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole

There total 5 articles about 2-(4-Methylphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 216483-12-4
4-methyl-benzoic acid N'-(4-nitro-benzoyl)-hydrazide

: 62507-52-2
2-(4-nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; for 6h; Heating;
DOI:10.1080/15421400600930409

Reference yield: 83.0%

: 122-04-3
4-nitro-benzoyl chloride

: 3619-22-5
p-toluic hydrazide

: 62507-52-2
2-(4-nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: 4-nitro-benzoyl chloride; p-toluic hydrazide; In 1,4-dioxane; at 20 ℃; for 0.5h;

With boron trifluoride diethyl etherate; In 1,4-dioxane; at 130 ℃; for 2h;
DOI:10.1081/SCC-100103993

Reference yield:

: 3619-22-5
p-toluic hydrazide

: 62507-52-2
2-(4-nitrophenyl)-5-(4-methylphenyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / acetonitrile / 6 h / 23 °C

2: 71 percent / thionyl chloride / 2 h / Heating

With thionyl chloride; In acetonitrile;
DOI:10.1080/10426500600919074