2-AMINOPENTANE

Base Information

• Chemical Name: 2-AMINOPENTANE
• CAS No.: 625-30-9
• Molecular Formula: C5H13N
• Molecular Weight: 87.1649
• Mol file: 625-30-9.mol

Synonyms:2-Amino-pentadecansaeure;2-amino-pentadecanoic acid;2-pentylamine;2-amino-pentane;2-Pentanamine;pentyl-2-amine;1-methyl-butylamine;sec.-amylamine;2-AMYLAMINE;Pentadecanoic acid,2-amino;

Chemical Property of 2-AMINOPENTANE

Chemical Property:

• Vapor Pressure: 51.1mmHg at 25°C
• Melting Point: -70°C (estimate)
• Refractive Index: n20/D 1.4020(lit.)
• Boiling Point: 92.7oC at 760 mmHg
• Flash Point: 35oC
• PSA: 26.02000
• Density: 0.757g/cm3
• LogP: 1.83400

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINOPENTANE

There total 60 articles about 2-AMINOPENTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.4%

4-methoxybenzyl methyl ketone (122-84-9) + 2-Pentanone (107-87-9) → (R)‐2‐aminopentane (625-30-9,33985-20-5,54542-13-1,63493-28-7) + (R)-(-)-p-methoxyamphetamine (58993-79-6,23239-32-9)

Guidance literature:

With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase; ammonium formate; nicotinamide adenine dinucleotide; In aq. buffer; at 30 ℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;

DOI:10.1021/acs.joc.9b02445

Reference yield:

C36H60O30*C5H13N → 2-pentylamine (625-30-9) + alpha cyclodextrin (10016-20-3)

Guidance literature:

With phosphate buffer; In water-d2; at 25 ℃; Equilibrium constant; Thermodynamic data; standard molar enthalpy Δ_rH⁰, standard molar Gibbs energy Δ_rG⁰, standard molar entropy Δ_rS⁰;

DOI:10.1021/jp962715n

Reference yield:

2-Pentanone (107-87-9) + benzylamine (100-46-9) → benzaldehyde (100-52-7) + 2-pentylamine (625-30-9)

Guidance literature:

With S-selective ω-transaminase from paracoccus denitrificans transaminase; NAD; aldehyde dehydrogenase; In dimethyl sulfoxide; Reagent/catalyst; Enzymatic reaction;

DOI:10.1002/cctc.201900399

upstream raw materials:

pentan-2-one oxime

1,2-di(pentan-2-ylidene)hydrazine

2-nitropentane

pentan-2-one-phenylhydrazone

Downstream raw materials:

2-acetamidopentane

N-(1-methyl-butyl)-N'-phenyl-urea

N-ethyl-N-isopropyl-N'-phenyl-thiourea

1-(2,6-Diethyl-cyclohexyl)-3-(1-methyl-butyl)-thiourea

Refernces

• 1、 Tseliou, Vasilis,Schilder, Don,Masman, Marcelo F.,Knaus, Tanja,Mutti, Francesco G.. "Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity". supporting information. p. 3315 - 3325. Retrieved 2020/12/11.
• 2、 B?umler, Christoph,Bauer, Christof,Kempe, Rhett. "The Synthesis of Primary Amines through Reductive Amination Employing an Iron Catalyst". . p. 3110 - 3114. Retrieved 2020/06/01.