Benzoyl chloride, 4-chloro-3-(chlorosulfonyl)-

Base Information

• Chemical Name: Benzoyl chloride, 4-chloro-3-(chlorosulfonyl)-
• CAS No.: 62574-66-7
• Molecular Formula: C7H3Cl3O3S
• Molecular Weight: 273.524
• Mol file: 62574-66-7.mol

Synonyms:4-Chlor-3-chlorsulfonyl-benzoylchlorid;

Chemical Property of Benzoyl chloride, 4-chloro-3-(chlorosulfonyl)-

Chemical Property:

• Melting Point: 42-43 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 136-138 °C(Press: 1.5 Torr)
• PSA: 59.59000
• Density: 1.663±0.06 g/cm3(Predicted)
• LogP: 3.72730

Purity/Quality:

99% ^*data from raw suppliers

4-Chloro-3-(chlorosulfonyl)benzoyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoyl chloride, 4-chloro-3-(chlorosulfonyl)-

There total 5 articles about Benzoyl chloride, 4-chloro-3-(chlorosulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-chloro-3-(chlorosulfonyl)benzoic acid (2494-79-3) → 3-chlorosulfonyl-4-chlorobenzoyl chloride (62574-66-7)

Guidance literature:

With thionyl chloride; In benzene; for 8h; Heating;

DOI:10.1246/bcsj.63.2010

Reference yield:

4-chlorotrichloromethylbenzene (5216-25-1) → 3-chlorosulfonyl-4-chlorobenzoyl chloride (62574-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfuric acid / 1) 120 deg C, 1 h 2) 150 deg C, 2 h

2: 94 percent / SOCl₂ / benzene / 8 h / Heating

With thionyl chloride; chlorosulphuric acid; In benzene;

DOI:10.1246/bcsj.63.2010

Reference yield:

para-chlorobenzoic acid (74-11-3) → 3-chlorosulfonyl-4-chlorobenzoyl chloride (62574-66-7)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfonic acid / 0 - 130 °C

2: thionyl chloride / toluene / 14 h / Inert atmosphere; Reflux

With chlorosulfonic acid; thionyl chloride; In toluene;

upstream raw materials:

4-chloro-3-(chlorosulfonyl)benzoic acid

4-chlorotrichloromethylbenzene

para-chlorobenzoic acid

Downstream raw materials:

2-chloro-5-(dimethylcarbamoyl)benzene-1-sulfonyl chloride

Refernces

• 1、 -. "Bis-Acylated Hydroxylamine Derivatives". Page/Page column 38. . Retrieved 2011/06/24.