Technology Process of L-Serine, N-[N-[[(4-methoxyphenyl)methoxy]carbonyl]-L-valyl]-, methyl
ester
There total 1 articles about L-Serine, N-[N-[[(4-methoxyphenyl)methoxy]carbonyl]-L-valyl]-, methyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dicyclohexyl-carbodiimide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
1) 3 h, 0 deg C; 2) 15 h, room temperature;
DOI:10.1248/cpb.30.1706
- Guidance literature:
-
Multi-step reaction with 3 steps
1: anisole / 1 h / 0 °C
2: 2) triethylamine / 2) DMF, 4 deg C, 48 h
3: 81 percent / 80percent hydrazine hydrate / methanol; dimethylformamide
With
hydrazine hydrate; methoxybenzene; triethylamine;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.30.1706
- Guidance literature:
-
Multi-step reaction with 6 steps
1: trifluoroacatic acid, anisole
2: 88 percent / Et3N / dimethylformamide / Ambient temperature
3: trifluoroacetic acid, anisole
4: 76 percent / Et3N / tetrahydrofuran; dimethylformamide / 5 h
5: 88 percent / 80 percent hydrazine hydrate / dimethylformamide
6: isoamyl nitrite / 4 °C
With
hydrazine hydrate; methoxybenzene; triethylamine; trifluoroacetic acid; isopentyl nitrite;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1248/cpb.35.1076
