3-Benzyl-4-hydroxy-4-phenylbutan-2-one

Base Information

Chemical Name:3-Benzyl-4-hydroxy-4-phenylbutan-2-one
CAS No.:62730-80-7
Molecular Formula:C17H18O2
Molecular Weight:254.329
Hs Code.:
DSSTox Substance ID:DTXSID70499326
Nikkaji Number:J2.570.337E

Synonyms:3-benzyl-4-hydroxy-4-phenylbutan-2-one;62730-80-7;DTXSID70499326;3-benzyl-4-hydroxy-4-phenyl-2-butanone

Suppliers and Price of 3-Benzyl-4-hydroxy-4-phenylbutan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Benzyl-4-hydroxy-4-phenylbutan-2-one

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:254.130679813
Heavy Atom Count:19
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C(CC1=CC=CC=C1)C(C2=CC=CC=C2)O

Technology Process of 3-Benzyl-4-hydroxy-4-phenylbutan-2-one

There total 10 articles about 3-Benzyl-4-hydroxy-4-phenylbutan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1024022-50-1
2-benzyl-1-hydroxy-1,1-diphenyl-3-butanone

: 100-52-7
benzaldehyde

: 62730-80-7
2-benzyl-1-hydroxy-1-phenyl-3-butanone

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; caesium carbonate; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In 1,4-dioxane; at 20 ℃; for 3h;
DOI:10.1016/j.tetlet.2008.02.062

Reference yield: 86.0%

: 66581-82-6
4-phenyl-3-(trimethylsilyl)-2-butanone

: 100-52-7
benzaldehyde

: 62730-80-7
2-benzyl-1-hydroxy-1-phenyl-3-butanone

Guidance literature:: With boron trifluoride diethyl etherate; In dichloromethane; Product distribution; 1.) 1 h, -78 deg C 2.) 30 min, -40 deg C; use of different Lewis acids : TiCl₄, SnCl₄, Bu₄F (3 h at -40 deg C); reaction starting with other ketones;
DOI:10.1021/jo00198a017

Reference yield: 48.0%

: 92694-79-6
4-phenyl-1-(trimethylsilyl)-2-butanone

: 100-52-7
benzaldehyde

: 5396-91-8
1,5-diphenyl-3-pentanone

: 62510-08-1
1,5-diphenyl-1-penten-3-one

: 62730-80-7
2-benzyl-1-hydroxy-1-phenyl-3-butanone

Guidance literature:: With lithium diisopropyl amide; Yield given. Multistep reaction; 1. THF, -70 deg C, 15 min 2. 10 s;
DOI:10.1021/jo00198a017