1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-

Base Information

Chemical Name:1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-
CAS No.:62746-77-4
Molecular Formula:C12H14FIO2
Molecular Weight:336.14100
Hs Code.:
DSSTox Substance ID:DTXSID70438376
Wikidata:Q82254101

Synonyms:62746-77-4;1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-;DTXSID70438376

Suppliers and Price of 1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-

Chemical Property:

PSA：18.46000
LogP:3.24050
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:336.00226
Heavy Atom Count:16
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(O1)(CCCI)C2=CC=C(C=C2)F

Technology Process of 1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)-

There total 2 articles about 1,3-Dioxolane, 2-(4-fluorophenyl)-2-(3-iodopropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 107-21-1
ethylene glycol

: 40862-32-6
1-iodo-3-(p-fluorophenylcarbonyl)propane

: 62746-77-4
2-(4-fluorophenyl)-2-(3-iodopropyl)-1,3-dioxolane

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 7.5h; Heating;

Reference yield:

: 3874-54-2,41167-07-1
4-(4-fluorophenyl)-4-oxo-n-butyl chloride

: 62746-77-4
2-(4-fluorophenyl)-2-(3-iodopropyl)-1,3-dioxolane

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / NaI / butan-2-one / 3 h / Heating

2: 99 percent / TsOH*H₂O / benzene / 7.5 h / Heating

With toluene-4-sulfonic acid; sodium iodide; In butanone; benzene;

Reference yield:

: 62746-77-4
2-(4-fluorophenyl)-2-(3-iodopropyl)-1,3-dioxolane

: 168907-75-3
1-(4-fluorophenyl)-4-(1-methyl-2-imidazolyl)-1-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) BuLi / 1.) THF, hexane, -40 deg C, 15 min, 2.) THF, hexane, -40 deg C, 2 h

2: 100 percent / aq. HCl / methanol / 4.5 h / Heating

With hydrogenchloride; n-butyllithium; In methanol;