tert-Butyl-dimethyl-o-tolyloxy-silane

Base Information

• Chemical Name: tert-Butyl-dimethyl-o-tolyloxy-silane
• CAS No.: 62790-79-8
• Molecular Formula: C13H22OSi
• Molecular Weight: 222.403
• DSSTox Substance ID: DTXSID30461963
• Nikkaji Number: J1.052.566G
• Wikidata: Q82286424
• Mol file: 62790-79-8.mol

Synonyms:tert-Butyl-dimethyl-o-tolyloxy-silane;2-Cresol tbdms;62790-79-8;o-Cresol, TBDMS derivative;SCHEMBL2329763;DTXSID30461963;(1,1-dimethylethyl)dimethyl(2-methylphenoxy)silane

Chemical Property of tert-Butyl-dimethyl-o-tolyloxy-silane

Chemical Property:

• PSA: 9.23000
• LogP: 4.37900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 222.143991855
• Heavy Atom Count: 15
• Complexity: 205

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1O[Si](C)(C)C(C)(C)C

Technology Process of tert-Butyl-dimethyl-o-tolyloxy-silane

There total 4 articles about tert-Butyl-dimethyl-o-tolyloxy-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyldimethylsilyl chloride (18162-48-6) + ortho-cresol (95-48-7,77504-84-8) → 2-(tert-butyldimethylsilyloxy)toluene (62790-79-8)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; for 3h;

Reference yield: 99.0%

2-methylphenyl bromide (95-46-5) + sodium tert-butyldimethylsiloxide → 2-(tert-butyldimethylsilyloxy)toluene (62790-79-8)

Guidance literature:

With monophosphine 1,2,3,4,5-pentaphenyl-1'-(di-tert-butylphosphino)ferrocene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 20 ℃; for 15h;

DOI:10.1021/ja002543e

Reference yield: 99.0%

→ 2-(tert-butyldimethylsilyloxy)toluene (62790-79-8)

Guidance literature:

upstream raw materials:

tert-butyldimethylsilyl chloride

ortho-cresol

2-methylphenyl acetate

t-butyldimethylsiyl triflate

Downstream raw materials:

2-((tert-butyldimethylsilyl)oxy)benzyl bromide

ortho-cresol

o-[4-hydroxy-3-methyl-2(Z)-butenyl]phenol

tert-butyl-dimethyl-{2-[3-methyl-4-(tetrahydro-pyran-2-yloxy)-but-2-enyl]-phenoxy}-silane