2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-

Base Information

Chemical Name:2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-
CAS No.:62806-35-3
Molecular Formula:C13H9BrO3
Molecular Weight:293.11300
Hs Code.:2932190090
DSSTox Substance ID:DTXSID50353553

Synonyms:2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-;3-[5-(4-bromophenyl)furan-2-yl]prop-2-enoic acid;ChemDiv3_001300;CBDivE_001286;DTXSID50353553;AKOS030230054

Suppliers and Price of 2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(E)-3-(5-(4-bromophenyl)furan-2-yl)acrylicacid 95+%
1g
$ 583.00

Total 3 raw suppliers

Chemical Property of 2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-

Chemical Property:

Melting Point:198-199 °C(Solv: benzene (71-43-2))
Boiling Point:436.8±40.0 °C(Predicted)
PSA：50.44000
Density:1.548±0.06 g/cm3(Predicted)
LogP:3.80690
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:291.97351
Heavy Atom Count:17
Complexity:295

Purity/Quality:

99% ^*data from raw suppliers

(E)-3-(5-(4-bromophenyl)furan-2-yl)acrylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC=C(O2)C=CC(=O)O)Br

Technology Process of 2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)-

There total 12 articles about 2-Propenoic acid, 3-[5-(4-bromophenyl)-2-furanyl]-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 141-82-2
malonic acid

: 20005-42-9
5-(4-bromophenyl)-2-furancarboxyaldehyde

: 62806-35-3
(E)-3-(5-(4-bromophenyl)furan-2-yl)acrylic acid

Guidance literature:: With piperidine; pyridine; for 4h; Heating;

Reference yield: 45.0%

: rac-2-amino-3-(5-(4-bromophenyl)furan-2-yl)propanoic acid

: C₁₃H₁₂BrNO₃

: 62806-35-3
(E)-3-(5-(4-bromophenyl)furan-2-yl)acrylic acid

Guidance literature:: With phenylalanine ammonia-lyase; at 30 ℃; for 192h; pH=8.8; optical yield given as %ee; enantioselective reaction; aq. buffer; Inert atmosphere; Enzymatic reaction;
DOI:10.3987/COM-10-S(E)60

Reference yield:

: 1899-24-7
5-bromo-2-furancarboxaldehyde

: 62806-35-3
(E)-3-(5-(4-bromophenyl)furan-2-yl)acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (Ph₃P)4Pd; aq. K₂CO₃ / toluene; ethanol / 5 h / Heating

2: pyridine; piperidine / 2 h / Heating

With piperidine; pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In ethanol; toluene; 1: Suzuki coupling;
DOI:10.1016/S0960-894X(02)00555-3