resorstatin

Base Information

• Chemical Name: resorstatin
• CAS No.: 139552-96-8
• Molecular Formula: C17H28 O2
• Molecular Weight: 264.4
• Mol file: 139552-96-8.mol

Synonyms:KDC 165;Resorstatin

Chemical Property of resorstatin

Chemical Property:

• Vapor Pressure: 3.46E-07mmHg at 25°C
• Boiling Point: 406.5°C at 760 mmHg
• Flash Point: 183.3°C
• PSA: 40.46000
• Density: 0.988g/cm³
• LogP: 4.95330

Purity/Quality:

≥98% （HPLC） ^*data from raw suppliers

RESORSTATIN 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of resorstatin

There total 5 articles about resorstatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-Hexyl-1,3-dimethoxy-5-pentyl-benzene (198206-79-0) → resorstatin [2-hexyl-5-pentylbenzene-1,3-diol] (139552-96-8)

Guidance literature:

With boron tribromide; In dichloromethane; at 25 ℃; for 2h;

DOI:10.1080/00397919708007301

Reference yield:

3,5-dimethoxybenzyl alcohol (705-76-0) → resorstatin [2-hexyl-5-pentylbenzene-1,3-diol] (139552-96-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) MeLi / 1.) THF, ether, -10 deg C, 0.5 h, 2.) THF, -10 deg C, 1 h.

2: 91 percent / tetrahydrofuran; hexane / 0.17 h / -10 °C

3: 1.) tert-BuLi / 1.) pentane, THF, -10 deg C, 1 h, 2.) THF, reflux, 2 h.

4: 98 percent / BBr₃ / CH₂Cl₂ / 2 h / 25 °C

With methyllithium; tert.-butyl lithium; boron tribromide; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1080/00397919708007301

Reference yield:

1,3-dimethoxy-5-pentylbenzene (22976-40-5) → resorstatin [2-hexyl-5-pentylbenzene-1,3-diol] (139552-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) tert-BuLi / 1.) pentane, THF, -10 deg C, 1 h, 2.) THF, reflux, 2 h.

2: 98 percent / BBr₃ / CH₂Cl₂ / 2 h / 25 °C

With tert.-butyl lithium; boron tribromide; In dichloromethane;

DOI:10.1080/00397919708007301

upstream raw materials:

2-Hexyl-1,3-dimethoxy-5-pentyl-benzene

3,5-dimethoxybenzyl alcohol

1,3-dimethoxy-5-pentylbenzene

3,5-dimethoxybenzoic acid

Downstream raw materials:

2-hexyl-3-hydroxy-5-pentylbenzo-1,4-quinone