2-Methyl-1-(4-methylphenyl)prop-2-en-1-one

Base Information

• Chemical Name: 2-Methyl-1-(4-methylphenyl)prop-2-en-1-one
• CAS No.: 62834-89-3
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• DSSTox Substance ID: DTXSID10531572
• Nikkaji Number: J30.888I
• Wikidata: Q82403535
• Mol file: 62834-89-3.mol

Synonyms:62834-89-3;2-Methyl-1-(4-methylphenyl)prop-2-en-1-one;2-Methyl-1-(p-tolyl)-2-propenone;2-Propen-1-one, 2-methyl-1-(4-methylphenyl)-;2-Methyl-1-p-tolyl-propenone;SCHEMBL2816739;DTXSID10531572;MFCD20921195;AKOS017742300;2-Methyl-1-(p-tolyl)prop-2-en-1-one;SY312276;CS-0245157;G61220;EN300-3003945

Chemical Property of 2-Methyl-1-(4-methylphenyl)prop-2-en-1-one

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 160.088815002
• Heavy Atom Count: 12
• Complexity: 185

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(=O)C(=C)C

Technology Process of 2-Methyl-1-(4-methylphenyl)prop-2-en-1-one

There total 11 articles about 2-Methyl-1-(4-methylphenyl)prop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

→ 2-methyl-1-(p-tolyl)prop-2-en-1-one (62834-89-3)

Guidance literature:

With sodium tetrachloroaurate(III) dihyrate; In dimethyl sulfoxide; at 100 ℃; for 2h;

Reference yield: 78.0%

C14H22OSi → 2-methyl-1-(p-tolyl)prop-2-en-1-one (62834-89-3)

Guidance literature:

With tetrabutyl ammonium fluoride; oxygen; potassium acetate; palladium diacetate; In N,N-dimethyl acetamide; toluene; at 100 ℃;

DOI:10.1039/c2cc16758a

Reference yield: 66.0%

Tolperisone hydrochloride (67499-62-1,67499-63-2) → 2-methyl-1-(p-tolyl)prop-2-en-1-one (62834-89-3) + 1-(2-methyl-3-(4-methylphenyl)-3-oxopropyl)-2-piperidinone

Guidance literature:

With water; oxygen; sodium hydroxide; In 1,4-dioxane; at 80 ℃; for 24h; under 760.051 Torr; regioselective reaction; Green chemistry;

DOI:10.1002/anie.201602695

upstream raw materials:

2-bromoprop-1-ene

p-Toluic acid

formaldehyd

4'-methylpropiophenone

Downstream raw materials:

((Z)-3-Iodo-2-methyl-1-p-tolyl-propenyloxy)-trimethyl-silane

(3-Iodomethyl-3,5-dimethyl-2,6-di-p-tolyl-3,4-dihydro-2H-pyran-2-yloxy)-trimethyl-silane

1-(4-methyl-phenyl)-2-methylallyl alcohol

C₂₉H₃₄N₂O