Benzenemethanol, a-[(1Z)-2-phenylethenyl]-

Base Information

• Chemical Name: Benzenemethanol, a-[(1Z)-2-phenylethenyl]-
• CAS No.: 62839-70-7
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.276
• Mol file: 62839-70-7.mol

Synonyms:α-phenyl cinnamyl alcohol;α-phenylcinnamyl alcohol;1,3-diphenyl-2-propen-1-ol;1,3-diphenyl-prop-2-en-1-ol;1,3-diphenyl-1-propen-3-ol;1,3-diphenyl-3-hydroxypropene;

Chemical Property of Benzenemethanol, a-[(1Z)-2-phenylethenyl]-

Chemical Property:

• Boiling Point: 158-160 °C(Press: 4 Torr)
• PSA: 20.23000
• Density: 1.0638 g/cm3
• LogP: 3.43340

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenemethanol, a-[(1Z)-2-phenylethenyl]-

There total 64 articles about Benzenemethanol, a-[(1Z)-2-phenylethenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzalacetophenone (94-41-7) → 1,3-diphenyl-3-hydroxypropene (4663-33-6,62668-02-4,62839-70-7,116127-91-4,132014-29-0,136981-81-2,148616-45-9)

Guidance literature:

With silica gel; sodium cyanoborohydride; for 0.0208333h; regioselective reaction; Neat (no solvent); Microwave irradiation;

DOI:10.5012/bkcs.2010.31.10.2961

Reference yield: 96.0%

1,3-diphenyl-1-propyn-3-ol (1817-49-8) → (2Z)-1,3-diphenyl-2-propen-1-ol (62839-70-7,1003558-27-7)

Guidance literature:

With hydrogen; Pd-C on CaCO₃-BaSO₄; In ethanol; for 4.5h;

DOI:10.1039/P29860000923

Reference yield: 95.0%

3-phenyl-propenal (104-55-2) + phenylboronic acid (98-80-6) → 1,3-diphenyl-3-hydroxypropene (4663-33-6,62668-02-4,62839-70-7,116127-91-4,132014-29-0,136981-81-2,148616-45-9)

Guidance literature:

With Rh₂(trifluoroacetate)₄(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)₂; potassium tert-butylate; In methanol; at 65 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tet.2010.08.050

upstream raw materials:

aluminum ethoxide

benzalacetophenone

3-bromro-1,3-diphenyl-1-propene

trans-1-benzylsulfonyl-2-phenylethene

Downstream raw materials:

dihydrochalcone

3-acetoxy-1,3-diphenylpropene

1-Dimethylamino-1,3-diphenyl-2-propen

1,3-Diphenylallyl-phenylsulfid

Refernces

• 1、 Singh, Bara,Bankar, Siddheshwar K.,Ramasastry. "Pd-Catalyzed Nazarov-Type Cyclization: Application in the Total Synthesis of β-Diasarone and Other Complex Cyclopentanoids". supporting information. p. 1043 - 1048. Retrieved 2022/02/05.
• 2、 Ai, Jing-Jing,Li, Jian,Ji, Shun-Jun,Wang, Shun-Yi. "One-pot two-step reaction of selenosulfonate with isocyanides and allyl alcohol under aqueous conditions: Atom-economic synthesis of selenocarbamates and allyl sulfones". supporting information. p. 721 - 724. Retrieved 2020/07/24.