3-Ethoxy-6-methyl-2-cyclohexen-1-one

Base Information

Chemical Name:3-Ethoxy-6-methyl-2-cyclohexen-1-one
CAS No.:62952-33-4
Molecular Formula:C9H14O2
Molecular Weight:154.209
Hs Code.:
DSSTox Substance ID:DTXSID90450757
Nikkaji Number:J892.380I

Synonyms:3-ethoxy-6-methyl-2-cyclohexen-1-one;3-ethoxy-6-methylcyclohex-2-en-1-one;62952-33-4;SCHEMBL4773759;DTXSID90450757;LVCINSLLJIHISO-UHFFFAOYSA-N;1-Ethoxy-4-methylcyclohexen-3-one

Suppliers and Price of 3-Ethoxy-6-methyl-2-cyclohexen-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Ethoxy-6-methyl-2-cyclohexen-1-one

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:154.099379685
Heavy Atom Count:11
Complexity:182

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC(=O)C(CC1)C

Technology Process of 3-Ethoxy-6-methyl-2-cyclohexen-1-one

There total 2 articles about 3-Ethoxy-6-methyl-2-cyclohexen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 5323-87-5
3-Ethoxycyclohex-2-en-1-one

: 74-88-4
methyl iodide

: 62952-33-4
3-ethoxy-6-methylcyclohex-2-en-1-one

Guidance literature:: 3-Ethoxycyclohex-2-en-1-one; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

methyl iodide; In tetrahydrofuran; hexane; at -78 - 25 ℃; for 1h;
DOI:10.1002/anie.200504421

Reference yield:

: 504-02-9
1,3-cylohexanedione

: 62952-33-4
3-ethoxy-6-methylcyclohex-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene-4-sulfonic acid / toluene / 8 h / 110 °C / Inert atmosphere

2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere

2.2: -70 - 20 °C / Inert atmosphere

With n-butyllithium; toluene-4-sulfonic acid; diisopropylamine; In tetrahydrofuran; hexane; toluene;
DOI:10.1021/acs.orglett.6b03394

Reference yield: 97.0%

: 62952-33-4
3-ethoxy-6-methylcyclohex-2-en-1-one

: 4-chloro-5-ethoxy-2-methylphenol

Guidance literature:: 3-ethoxy-6-methylcyclohex-2-en-1-one; With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

With p-toluenesulfonyl chloride; lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 22 ℃; for 1h; Inert atmosphere;
DOI:10.1021/ol503561x