Technology Process of Benzenamine,
N-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-N-methyl-4-[2-(2-thienyl)
ethenyl]-
There total 10 articles about Benzenamine,
N-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-N-methyl-4-[2-(2-thienyl)
ethenyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 125 °C
2: sodium hydride / 1,2-dimethoxyethane
With
sodium hydride;
In
1,2-dimethoxyethane;
2: |Vilsmeier-Haack Formylation;
DOI:10.1016/j.dyepig.2015.02.026
- Guidance literature:
-
With
1H-imidazole;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1.5h;
DOI:10.1002/pola.24410
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trichlorophosphate / 0 - 20 °C / Inert atmosphere
2: phenyllithium / tetrahydrofuran; dibutyl ether / 1.5 h / 0 °C / Inert atmosphere
3: water; sodium hydroxide / ethanol / 1 h / 40 °C
4: 1H-imidazole / N,N-dimethyl-formamide / 1.5 h / 20 °C
With
1H-imidazole; water; phenyllithium; sodium hydroxide; trichlorophosphate;
In
tetrahydrofuran; ethanol; dibutyl ether; N,N-dimethyl-formamide;
2: Wittig reaction;
DOI:10.1002/pola.24410
