p-(Phenylazo)benzyl chloroformate

Base Information

• Chemical Name: p-(Phenylazo)benzyl chloroformate
• CAS No.: 55592-99-9
• Molecular Formula: C14H11 Cl N2 O2
• Molecular Weight: 274.707
• European Community (EC) Number: 259-719-5
• DSSTox Substance ID: DTXSID601200346
• Nikkaji Number: J267.031C
• Mol file: 55592-99-9.mol

Synonyms:p-(Phenylazo)benzyl chloroformate;55592-99-9;EINECS 259-719-5;SCHEMBL3291946;DTXSID601200346;4-phenylazobenzyloxycarbonyl chloride;Chloroformic acid [4-(phenylazo)phenyl]methyl ester;Carbonochloridic acid, [4-(phenylazo)phenyl]methyl ester

Chemical Property of p-(Phenylazo)benzyl chloroformate

Chemical Property:

• Vapor Pressure: 1.07E-06mmHg at 25°C
• Boiling Point: 402.8°Cat760mmHg
• Flash Point: 197.4°C
• PSA: 51.02000
• Density: 1.22g/cm³
• LogP: 4.97740
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 274.0509053
• Heavy Atom Count: 19
• Complexity: 309

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)N=NC2=CC=C(C=C2)COC(=O)Cl

Technology Process of p-(Phenylazo)benzyl chloroformate

There total 3 articles about p-(Phenylazo)benzyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 1-(4-(hydroxymethyl)phenyl)-2-phenyldiazene (65926-74-1) → PAZ-Cl (55592-99-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/S0960-894X(01)00464-4

Reference yield:

phosgene (75-44-5) + 1-(4-(hydroxymethyl)phenyl)-2-phenyldiazene (65926-74-1) → PAZ-Cl (55592-99-9)

Guidance literature:

Reference yield:

→ PAZ-Cl (55592-99-9)

Guidance literature:

entspr. Benzylalkohol 1, COCl2;

upstream raw materials:

phosgene

1-(4-(hydroxymethyl)phenyl)-2-phenyldiazene

bis(trichloromethyl) carbonate

Downstream raw materials:

PAZ-Gly-OH

PAZ-Gly-D-Phe-Ala-OMe

<(p-Phenylazo-benzyloxycarbonyl-(DL-α-phenyl-alanin)>-pivalinsaeureanhydrid

N^α-(4-Phenylazo-benzyloxycarbonyl)-L-tryptophan

Refernces