1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine

Base Information

Chemical Name:1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine
CAS No.:63178-61-0
Molecular Formula:C11H15N3O4S
Molecular Weight:285.324
Hs Code.:
DSSTox Substance ID:DTXSID30385418
Wikidata:Q82178197

Synonyms:1-(methylsulfonyl)-4-(4-nitrophenyl)piperazine;63178-61-0;1-methylsulfonyl-4-(4-nitrophenyl)piperazine;1-methanesulfonyl-4-(4-nitrophenyl)piperazine;ST088463;4-(4-nitrophenyl)-1-methylsulfonylpiperazine;Oprea1_632067;CBDivE_007430;SCHEMBL2719030;DTXSID30385418;VIIQBVNBFQUOTO-UHFFFAOYSA-N;MFCD00425584;STK070383;AKOS000423918;CS-0322772;4-(4 nitrophenyl)-1-methylsulfonylpiperazine;AB00017579-01;SR-01000530437;SR-01000530437-1

Suppliers and Price of 1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:285.07832714
Heavy Atom Count:19
Complexity:412

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine

There total 5 articles about 1-(Methylsulfonyl)-4-(4-nitrophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 6269-89-2
1-(4-Nitrophenyl)piperazine

: 124-63-0
methanesulfonyl chloride

: 63178-61-0
4-(4-nitrophenyl)-1-methylsulfonylpiperazine

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 5 ℃; for 1h;

Reference yield:

: 6269-89-2
1-(4-Nitrophenyl)piperazine

: 124-63-0
methanesulfonyl chloride

: 442549-42-0
4-(4-(methylsulfonyl)piperazin-1-yl)aniline

: 63178-61-0
4-(4-nitrophenyl)-1-methylsulfonylpiperazine

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield:

: 182618-86-6
tert-butyl 4-(4-nitrophenyl)piperazine-1-carboxylate

: 63178-61-0
4-(4-nitrophenyl)-1-methylsulfonylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

2: triethylamine / dichloromethane / 1 h / 0 - 5 °C

With triethylamine; trifluoroacetic acid; In dichloromethane;