(R)-1-(3-Chlorophenyl)-1,3-propanediol

Base Information

Chemical Name:(R)-1-(3-Chlorophenyl)-1,3-propanediol
CAS No.:632327-18-5
Molecular Formula:C9H11ClO2
Molecular Weight:186.638
Hs Code.:
Mol file:632327-18-5.mol

Synonyms:(R)-1-(3-Chloro-phenyl)-propane-1,3-diol;(R)-1-(3'-chlorophenyl)-1,3-dihydroxypropane;(R)-3-(3'-chlorophenyl)-1,3-dihydroxypropane;(R)-(+)-3-(3-chlorophenyl)-1,3-propanediol;(+)-(R)-1-(3-chlorophenyl)-1,3-propanediol;

Suppliers and Price of (R)-1-(3-Chlorophenyl)-1,3-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of (R)-1-(3-Chlorophenyl)-1,3-propanediol

Chemical Property:

PSA：40.46000
LogP:1.75580

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-1-(3-Chlorophenyl)-1,3-propanediol

There total 15 articles about (R)-1-(3-Chlorophenyl)-1,3-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.8%

: 804561-32-8
(2R,8R,11S)-2-(3-chlorophenyl)-8-methyl-11-(1-methylethyl)-1,5-dioxaspiro[5.5]undecane

: 632327-18-5
(R)-(+)-1-(3-chlorophenyl)-1,3-propanediol

Guidance literature:: With hydrogenchloride; water; In methanol; at 20 ℃;
DOI:10.1111/j.1747-0285.2010.01077.x

Reference yield: 67.0%

: 125617-30-3
rac-(3-(3-chlorophenyl)oxiran-2-yl)methanol

: 632327-18-5
(R)-(+)-1-(3-chlorophenyl)-1,3-propanediol

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In 1,2-dimethoxyethane; toluene; at 0 - 20 ℃; for 3h;

Reference yield:

: 51699-45-7
(S)-(-)-1-(3'-Chlorophenyl)-1,3-Propanediol

: 632327-18-5
(R)-(+)-1-(3-chlorophenyl)-1,3-propanediol

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / trimethylsilyl triflate / tetrahydrofuran / 1 h / 20 °C

2: 7.33 g / trimethylsilyltriflate / CH₂Cl₂ / 48 h / -50 °C

3: 75.4 percent / aq. HCl / methanol / 20 °C

With hydrogenchloride; trimethylsilyl trifluoromethanesulfonate; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja031818y