alpha-(3-Aminopropyl)benzenepropanoic acid

Base Information

Chemical Name:alpha-(3-Aminopropyl)benzenepropanoic acid
CAS No.:63378-72-3
Molecular Formula:C12H17NO2
Molecular Weight:207.272
Hs Code.:
DSSTox Substance ID:DTXSID801284459

Synonyms:alpha-(3-Aminopropyl)benzenepropanoic acid;SCHEMBL429946;DTXSID801284459;63378-72-3

Suppliers and Price of alpha-(3-Aminopropyl)benzenepropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of alpha-(3-Aminopropyl)benzenepropanoic acid

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:207.125928785
Heavy Atom Count:15
Complexity:188

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CCCN)C(=O)O

Technology Process of alpha-(3-Aminopropyl)benzenepropanoic acid

There total 4 articles about alpha-(3-Aminopropyl)benzenepropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 142178-62-9
α-<3-<<(1,1-dimethylethoxy)carbonyl>amino>propyl>benzenepropanoic acid

: 63378-72-3
2-benzyl-5-aminopentanoic acid

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; for 0.25h; Ambient temperature;
DOI:10.1021/jm00094a002

Reference yield:

: 100-39-0
benzyl bromide

: 63378-72-3
2-benzyl-5-aminopentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) lithium bis(trimethylsilylamide) (LHMDS) / 1.) THF, pentane, -78 deg C, 15 min, 2.) THF, pentane, from -78 deg C to 0 deg C, 2 h

2: 94 percent / aq. LiOH / tetrahydrofuran / 16 h / Ambient temperature

3: HCl / CH₂Cl₂; dioxane / 0.25 h / Ambient temperature

With hydrogenchloride; lithium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00094a002

Reference yield:

: 85908-96-9
2-oxopiperidine-1-carboxylic acid tert-butyl ester

: 63378-72-3
2-benzyl-5-aminopentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) lithium bis(trimethylsilylamide) (LHMDS) / 1.) THF, pentane, -78 deg C, 15 min, 2.) THF, pentane, from -78 deg C to 0 deg C, 2 h

2: 94 percent / aq. LiOH / tetrahydrofuran / 16 h / Ambient temperature

3: HCl / CH₂Cl₂; dioxane / 0.25 h / Ambient temperature

With hydrogenchloride; lithium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/jm00094a002