2H-Pyran-2-one, 3-acetyltetrahydro-

Base Information

Chemical Name:2H-Pyran-2-one, 3-acetyltetrahydro-
CAS No.:63872-58-2
Molecular Formula:C₇H₁₀O₃
Molecular Weight:142.155
Hs Code.:
DSSTox Substance ID:DTXSID30466039
Nikkaji Number:J46.554B

Synonyms:2H-Pyran-2-one, 3-acetyltetrahydro-;63872-58-2;SCHEMBL535757;DTXSID30466039;ALPHA-ACETYL DELTA-VALEROLACTONE

Suppliers and Price of 2H-Pyran-2-one, 3-acetyltetrahydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2H-Pyran-2-one, 3-acetyltetrahydro-

Chemical Property:

PSA：43.37000
LogP:0.52860
XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:142.062994177
Heavy Atom Count:10
Complexity:162

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCCOC1=O

Technology Process of 2H-Pyran-2-one, 3-acetyltetrahydro-

There total 1 articles about 2H-Pyran-2-one, 3-acetyltetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 100-52-7
benzaldehyde

: 331854-15-0
2-trimethylsilyloxy-3-[1-(trimethylsilyloxy)ethylidenyl]-5,6-dihydro-4H-pyran

: 63872-58-2
α-acetyl-δ-valerolactone

: 2-phenyl-2,3,6,7-tetrahydro-4H-pyran[2,3-b]-4H-pyran-4-one

Guidance literature:: With zinc(II) chloride; at 20 ℃; for 24h;
DOI:10.1021/jo0015319

Reference yield:

: 63872-58-2
α-acetyl-δ-valerolactone

: 2-phenyl-2,3,6,7-tetrahydro-4H-pyran[2,3-b]-4H-pyran-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / LDA / tetrahydrofuran / 1 h / -78 - 20 °C

2: 40 percent / ZnCl₂ / 24 h / 20 °C

With zinc(II) chloride; lithium diisopropyl amide; In tetrahydrofuran; 2: Diels-Alder reaction;
DOI:10.1021/jo0015319

Reference yield:

: 63872-58-2
α-acetyl-δ-valerolactone

: 120950-90-5
3-methyl-4-(3-hydroxypropyl)-cyclohex-2-en-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / tBuONa / CH₂Cl₂

2: 69 percent / pyrrolidine; AcOH / various solvent(s) / 16 h / 20 °C

3: 20 percent / KOH / tetrahydrofuran; H₂O / 16 h / 80 °C

With pyrrolidine; potassium hydroxide; acetic acid; sodium t-butanolate; In tetrahydrofuran; dichloromethane; water; 1: Michael reaction;
DOI:10.1002/ejoc.200300009