(Hydroxymethyl)triphenylphosphonium chloride

Base Information

• Chemical Name: (Hydroxymethyl)triphenylphosphonium chloride
• CAS No.: 5293-83-4
• Molecular Formula: C19H18 O P . Cl
• Molecular Weight: 328.778
• European Community (EC) Number: 226-138-3
• NSC Number: 221281
• DSSTox Substance ID: DTXSID30967399
• Mol file: 5293-83-4.mol

Synonyms:(Hydroxymethyl)triphenylphosphonium chloride;5293-83-4;hydroxymethyl triphenylphosphonium chloride;EINECS 226-138-3;hydroxymethyl(triphenyl)phosphanium;chloride;NSC 221281;C19H18ClOP;C19H18OP.Cl;SCHEMBL2451129;C19-H18-O-P.Cl;DTXSID30967399;MFCD00031688;NSC221281;AKOS015903609;P(CO)(c1ccccc1)(c2ccccc2)c3ccccc3;NSC-221281;FT-0604978;(Hydroxymethyl)(triphenyl)phosphanium chloride;D70117;A829316

Chemical Property of (Hydroxymethyl)triphenylphosphonium chloride

Chemical Property:

• Melting Point: 195-196°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 33.82000
• Density: g/cm³
• LogP: -0.06570
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 328.0783799
• Heavy Atom Count: 22
• Complexity: 253

Purity/Quality:

99% ^*data from raw suppliers

(HYDROXYMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.
• Hazard Codes: R36/37/38:Irritating to eyes, respiratory system and skin.
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[P+](CO)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]

Technology Process of (Hydroxymethyl)triphenylphosphonium chloride

There total 2 articles about (Hydroxymethyl)triphenylphosphonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + triphenylphosphine (603-35-0) → tricyclohexyl(hydroxymethyl)phosphonium tetrafluoroborate (5293-83-4)

Guidance literature:

With hydrogenchloride; In diethyl ether;

Reference yield:

→ tricyclohexyl(hydroxymethyl)phosphonium tetrafluoroborate (5293-83-4)

Guidance literature:

Aus Triphenylphosphin;

DOI:10.1016/0040-4020(75)80017-2

Reference yield: 92.0%

3,3-Dimethylacryloyl chloride (3350-78-5) + tricyclohexyl(hydroxymethyl)phosphonium tetrafluoroborate (5293-83-4) → [(3-methylbut-2-enoyloxy)methyl]triphenylphosphonium chloride (1042165-31-0)

Guidance literature:

In dichloromethane; for 16h; Heating;

DOI:10.1016/j.tet.2008.04.068

upstream raw materials:

formaldehyd

triphenylphosphine

Downstream raw materials:

Tributyl-hydroxymethyl-phosphonium; chloride

chloromethyltriphenylphosphonium chloride

(N-carbomethoxylaminomethyl)triphenylphosphonium chloride

[(3-methylbut-2-enoyloxy)methyl]triphenylphosphonium chloride

Refernces