4-CHLORO-NAPHTHALENE-1-SULFONYL CHLORIDE

Base Information

• Chemical Name: 4-CHLORO-NAPHTHALENE-1-SULFONYL CHLORIDE
• CAS No.: 64318-08-7
• Molecular Formula: C10H6 Cl2 O2 S
• Molecular Weight: 261.128
• Hs Code.: 2904909090
• Mol file: 64318-08-7.mol

Synonyms:4-Chloro-1-naphthalenesulfonylchloride; NSC 77051

Chemical Property of 4-CHLORO-NAPHTHALENE-1-SULFONYL CHLORIDE

Chemical Property:

• Vapor Pressure: 4.71E-05mmHg at 25°C
• Boiling Point: 360.1°Cat760mmHg
• Flash Point: 171.6°C
• PSA: 42.52000
• Density: 1.516g/cm³
• LogP: 4.50150

Purity/Quality:

99% ^*data from raw suppliers

4-Chloronaphthalene-1-sulfonylchloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CHLORO-NAPHTHALENE-1-SULFONYL CHLORIDE

There total 4 articles about 4-CHLORO-NAPHTHALENE-1-SULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.13%

1-Chloronaphthalene (90-13-1) → 4-chloro-1-naphthalenesulfonyl chloride (64318-08-7)

Guidance literature:

With chlorosulfonic acid; In chloroform; at 0 - 5 ℃;

DOI:10.1016/j.ejmech.2010.01.008

Reference yield: 63.0%

→ 4-chloro-1-naphthalenesulfonyl chloride (64318-08-7)

Guidance literature:

Reference yield:

→ 4-chloro-1-naphthalenesulfonyl chloride (64318-08-7)

Guidance literature:

With phosphorus pentachloride;

upstream raw materials:

4-chloro-1-naphthylsulphonic acid

1-Chloronaphthalene

Downstream raw materials:

1-chloro-4-iodo-naphthalene

4-chloro-1-naphthylsulphonic acid

1,4-dichloronaphthalene

4-chloro-1-naphthalenesulfonyl-N-{2,3-dihydro-2,2-dimethyl-7-{2-[4-(2-methoxy-5-trifluoromethyl-phenyl)-piperazine]-ethoxy}-benzofuran-5-yl}-amide hydrochloride

Refernces

• 1、 Halder, Amit Kumar,Adhikary, Nilanjan,Maity, Milan Kumar,Jha, Tarun. "Synthesis, pharmacological activity and comparative QSAR modeling of 1,5-N,N′-substituted-2-(substituted naphthalenesulphonyl) glutamamides as possible anticancer agents". scheme or table. p. 1760 - 1771. Retrieved 2010/06/21.
• 2、 -. "Bispiperidines as antithrombotic agents". . . Retrieved 2008/06/13.