Benzo[c]phenanthren-2-ol

Base Information

Chemical Name:Benzo[c]phenanthren-2-ol
CAS No.:22717-94-8
Molecular Formula:C18H12 O
Molecular Weight:244.293
Hs Code.:2906299090
European Community (EC) Number:621-744-8
NSC Number:97676
UNII:605CPJ969J
DSSTox Substance ID:DTXSID50177251
Nikkaji Number:J1.558.908F
Wikidata:Q27225574
Metabolomics Workbench ID:74815
Mol file:22717-94-8.mol

Synonyms:Benzo[c]phenanthren-2-ol;Benzo(c)phenanthren-2-ol;22717-94-8;2-hydroxybenzo[c]phenanthrene;605CPJ969J;NSC 97676;NSC-97676;2-HYDROXYBENZO(C)PHENANTHRENE;NSC97676;2-benzo[c]phenanthrenol;Benzo(c)phenanthrene-2-ol;UNII-605CPJ969J;2-hydroxybenzo[c]-phenanthrene;DTXSID50177251;CHEBI:132443;AKOS024341208;Q27225574

Suppliers and Price of Benzo[c]phenanthren-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxybenzo[c]phenanthrene
25mg
$ 1045.00

Total 4 raw suppliers

Chemical Property of Benzo[c]phenanthren-2-ol

Chemical Property:

Vapor Pressure:1.5E-10mmHg at 25°C
Boiling Point:498.2°Cat760mmHg
Flash Point:240.4°C
PSA：20.23000
Density:1.284g/cm³
LogP:4.85180
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:244.088815002
Heavy Atom Count:19
Complexity:326

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-Hydroxybenzo[c]phenanthrene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC3=C2C4=C(C=C3)C=CC(=C4)O
Uses 2-Hydroxybenzo[c]phenanthrene is a metabolite of monohydroxy polycyclic aromatic hydrocarbon (PAH) toxin.

Technology Process of Benzo[c]phenanthren-2-ol

There total 12 articles about Benzo[c]phenanthren-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 4176-45-8
2-methoxy-benzo[c]phenanthrene

: 22717-94-8
2-hydroxybenzo[c]phenanthrene

Guidance literature:: With boron tribromide; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jacs.6b07424

Reference yield: 83.0%

: 2-(benzo[c]phenanthren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 22717-94-8
2-hydroxybenzo[c]phenanthrene

Guidance literature:: With N,N-dimethyl-p-toluidine N-oxide; In dichloromethane; at 23 ℃; for 5h;
DOI:10.1002/ejoc.201600979

Reference yield:

: 195-19-7
benzo[c]phenathrene

: 22717-94-8
2-hydroxybenzo[c]phenanthrene

Guidance literature:: Multi-step reaction with 2 steps

1: (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine / cyclohexane / 18 h / 23 °C / Inert atmosphere; Sealed tube

2: N,N-dimethyl-p-toluidine N-oxide / dichloromethane / 5 h / 23 °C

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; N,N-dimethyl-p-toluidine N-oxide; 4,4'-di-tert-butyl-2,2'-bipyridine; In dichloromethane; cyclohexane;
DOI:10.1002/ejoc.201600979