5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole

Base Information

• Chemical Name: 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole
• CAS No.: 64263-00-9
• Molecular Formula: C14H13N3
• Molecular Weight: 223.27300
• Mol file: 64263-00-9.mol

Synonyms:5,6-dimethyl-2-(4-pyridyl)-benzimidazole;5,6-Dimethyl-2-pyridin-4-yl-1H-benzoimidazole;5,6-Dimethyl-2--benzimidazol;5,6-Dimethyl-2-[4]pyridyl-1H-benzimidazol;2-(4'-Pyridyl)-5,6-dimethylbenzimidazol;

Chemical Property of 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole

Chemical Property:

• Melting Point: 241 - 243 °C
• PSA: 41.57000
• LogP: 3.24170

Purity/Quality:

99% ^*data from raw suppliers

5,6-Dimethyl-2-(pyridin-4-yl)-1H-benzo[D]imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole

There total 4 articles about 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

pyridine-4-carbaldehyde (872-85-5) + 4,5-dimethyl-1,2-phenylenediamine (3171-45-7) → 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole (64263-00-9)

Guidance literature:

With ammonium cerium (IV) nitrate; dihydrogen peroxide; at 50 ℃; for 1h;

DOI:10.3390/molecules18043972

Reference yield: 81.0%

pyridine-4-carboxylic acid (55-22-1) + 4,5-dimethyl-1,2-phenylenediamine (3171-45-7) → 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole (64263-00-9)

Guidance literature:

With PPA; Polyphosphoric acid (PPA); at 170 - 180 ℃; for 4h;

DOI:10.1055/s-1992-26121

Reference yield: 70.0%

picoline (108-89-4) + 4,5-dimethyl-2-nitrobenzenamine (6972-71-0) → 5,6-dimethyl-2-(pyridin-4-yl)-1H-benzo[d]imidazole (64263-00-9)

Guidance literature:

With iron; sulfur; at 150 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja311780a

upstream raw materials:

pyridine-4-carboxylic acid

4,5-dimethyl-1,2-phenylenediamine

picoline

4,5-dimethyl-2-nitrobenzenamine

Downstream raw materials:

C₂₁H₁₅FN₄

C₂₁H₁₅FN₄