Technology Process of N-Benzyl-2-Methoxy-N-MethylbenzaMide, 97%
There total 4 articles about N-Benzyl-2-Methoxy-N-MethylbenzaMide, 97% which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-methoxybenzoic acid methyl ester;
With
potassium phosphate; 2,2,2-trifluoroethanol;
In
1,4-dioxane;
at 125 ℃;
for 0.5h;
Sealed tube;
Schlenk technique;
Inert atmosphere;
benzyl-methyl-amine;
In
1,4-dioxane;
at 125 ℃;
for 22h;
Sealed tube;
Schlenk technique;
Inert atmosphere;
DOI:10.1039/c7ob00593h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
1.2: Inert atmosphere
1.3: 72 h / 45 °C / Inert atmosphere
2.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C / Inert atmosphere
3.1: 2,2,2-trifluoroethanol; potassium phosphate / 1,4-dioxane / 0.5 h / 125 °C / Sealed tube; Schlenk technique; Inert atmosphere
3.2: 22 h / 125 °C / Sealed tube; Schlenk technique; Inert atmosphere
With
potassium phosphate; 2,2,2-trifluoroethanol; triethylamine; trifluoroacetic acid;
In
1,4-dioxane; dichloromethane;
DOI:10.1039/c7ob00593h
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: trifluoroacetic acid / dichloromethane / 16 h / 20 °C / Inert atmosphere
2.1: 2,2,2-trifluoroethanol; potassium phosphate / 1,4-dioxane / 0.5 h / 125 °C / Sealed tube; Schlenk technique; Inert atmosphere
2.2: 22 h / 125 °C / Sealed tube; Schlenk technique; Inert atmosphere
With
potassium phosphate; 2,2,2-trifluoroethanol; trifluoroacetic acid;
In
1,4-dioxane; dichloromethane;
DOI:10.1039/c7ob00593h
