(E)-3-(phenylsulfonyl)acrylonitrile

Base Information

• Chemical Name: (E)-3-(phenylsulfonyl)acrylonitrile
• CAS No.: 64326-47-2
• Molecular Formula: C9H7NO2S
• Molecular Weight: 193.226
• Mol file: 64326-47-2.mol

Synonyms:(E)-3-(phenylsulfanyl)hex-3-ene;3-benzenesulfonyl-acrylonitrile;Benzene,[[(1E)-1-ethyl-1-butenyl]thio];(E)-3-phenylsulfonylprop-2-enenitrile;(E)-3-(phenylsulfonyl)acrylonitrile;(E)-3-phenylsulfanyl-3-hexene;3-phenylthio-3-hexene;(E)-3-(phenylthio)hex-3-ene;

Chemical Property of (E)-3-(phenylsulfonyl)acrylonitrile

Chemical Property:

• PSA: 66.31000
• LogP: 2.57838

Purity/Quality:

99% ^*data from raw suppliers

(E)-3-(Phenylsulfonyl)acrylonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-3-(phenylsulfonyl)acrylonitrile

There total 9 articles about (E)-3-(phenylsulfonyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

sodium benzenesulfonate (873-55-2) + 2-Chloroacrylonitrile (920-37-6) → (E)-β-cyanovinyl phenyl sulphone (64326-47-2)

Guidance literature:

With acetic acid; In water; for 0.333333h;

DOI:10.1021/acs.joc.8b02759

Reference yield: 80.0%

2,3-dibromopropionitrile (4554-16-9) + sodium benzenesulfonate (873-55-2) → (E)-β-cyanovinyl phenyl sulphone (64326-47-2)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃; for 10h;

DOI:10.1055/s-2007-966039

Reference yield: 71.0%

sodium benzenesulfonate (873-55-2) + acrylonitrile (107-13-1,25014-41-9) → (E)-β-cyanovinyl phenyl sulphone (64326-47-2)

Guidance literature:

sodium benzenesulfonate; With polystyrene-supported-SeCl; In N,N-dimethyl-formamide; at 20 ℃; for 6h; solid-phase reaction;

acrylonitrile; 2,2'-azobis(isobutyronitrile); In benzene; for 20h; Heating;

With dihydrogen peroxide; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1055/s-2001-18779

upstream raw materials:

2,3-dibromopropionitrile

sodium benzenesulfonate

acrylonitrile

benzenesulfonyl iodide

Downstream raw materials:

4-cyanophenol