2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione

Base Information

Chemical Name:2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione
CAS No.:93272-50-5
Molecular Formula:C₁₆H₁₆N₄O₅
Molecular Weight:344.327
Hs Code.:
NSC Number:358266
DSSTox Substance ID:DTXSID70320348

Synonyms:93272-50-5;NSC 358266;NSC358266;DTXSID70320348;2-[4-hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione;NSC-358266

Suppliers and Price of 2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione

Chemical Property:

Vapor Pressure:5.07E-16mmHg at 25°C
Boiling Point:615.8°Cat760mmHg
Flash Point:326.2°C
Density:1.5g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:344.11206962
Heavy Atom Count:25
Complexity:513

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CCCC(CN3C=CN=C3[N+](=O)[O-])O

Technology Process of 2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione

There total 4 articles about 2-[4-Hydroxy-5-(2-nitroimidazol-1-yl)pentyl]isoindole-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 527-73-1
2-nitro-1H-imidazole

: 93272-49-2
2-(3-(oxiran-2-yl)propyl)isoindoline-1,3-dione

: 93272-50-5
2-[4-Hydroxy-5-(2-nitro-imidazol-1-yl)-pentyl]-isoindole-1,3-dione

Guidance literature:: With potassium carbonate; In ethanol; for 4h; Heating;

Reference yield:

: 7736-25-6
2-(pent-4-enyl)-isoindoline-1,3-dione

: 93272-50-5
2-[4-Hydroxy-5-(2-nitro-imidazol-1-yl)-pentyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / 3-chloroperoxybenzoic acid, 3-tert-butyl-4-hydroxy-5-methylphenyl sulphide / 1,2-dichloro-ethane / 1.) RT, 2.) reflux

2: 56 percent / K₂CO₃ / ethanol / 4 h / Heating

With 6,6'-di-tert-butyl-4,4'-thiodi-o-cresol; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In ethanol; 1,2-dichloro-ethane;

Reference yield:

: 1074-82-4
potassium phtalimide

: 93272-50-5
2-[4-Hydroxy-5-(2-nitro-imidazol-1-yl)-pentyl]-isoindole-1,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / dimethylformamide / 100 - 120 °C

2: 75 percent / 3-chloroperoxybenzoic acid, 3-tert-butyl-4-hydroxy-5-methylphenyl sulphide / 1,2-dichloro-ethane / 1.) RT, 2.) reflux

3: 56 percent / K₂CO₃ / ethanol / 4 h / Heating

With 6,6'-di-tert-butyl-4,4'-thiodi-o-cresol; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In ethanol; 1,2-dichloro-ethane; N,N-dimethyl-formamide;