10-Bromocarbamazepine

Base Information

Chemical Name:10-Bromocarbamazepine
CAS No.:59690-97-0
Molecular Formula:C15H11BrN2O
Molecular Weight:315.169
Hs Code.:
Mol file:59690-97-0.mol

Synonyms:5H-Dibenz(b,f)azepine-5-carboxamide, 10-bromo-;

Suppliers and Price of 10-Bromocarbamazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide
50mg
$ 165.00

Crysdot
10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide 95%
11
$ 680.00

Crysdot
10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide 95%
250mg
$ 302.00

Alichem
10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide
1g
$ 707.20

Total 16 raw suppliers

Chemical Property of 10-Bromocarbamazepine

Chemical Property:

Vapor Pressure:9.35E-09mmHg at 25°C
Refractive Index:1.706
Boiling Point:463.091 °C at 760 mmHg
PKA:13.81±0.40(Predicted)
Flash Point:233.869 °C
PSA：47.32000
Density:1.584 g/cm³
LogP:4.68860
Storage Temp.:Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 10-Bromo-5H-dibenzo[b,f]azepine-5-carboxamide is a Carbamazepine (C175840(P)) impurity, which has been used in treatment of pain associated with trigeminal neuralgia. It is an anticonvulsant, neuroprotective & neuroresearch product.

Technology Process of 10-Bromocarbamazepine

There total 4 articles about 10-Bromocarbamazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 143667-53-2
10-Brom-5-chlorcarbonyl-5H-dibenzazepin

: 59690-97-0
10-Brom-5-carbamoyl-5H-dibenzazepin

Guidance literature:: With ammonia; In ethanol; at 40 - 60 ℃; for 8h;

Reference yield:

: 494-19-9
9,10-dihydrodibenzazepine

: 59690-97-0
10-Brom-5-carbamoyl-5H-dibenzazepin

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / chlorobenzene / 4 h / 100 - 115 °C

2: 2,2'-azobis(isobutyronitrile); sodium hydroxide; N-Bromosuccinimide / chlorobenzene / 12 h / 80 °C

3: ammonia / ethanol / 8 h / 40 - 60 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); ammonia; sodium hydroxide; In ethanol; chlorobenzene;

Reference yield:

: 33948-19-5
10,11-dihydro-dibenzo[b,f]azepine-5-carbonyl chloride

: 59690-97-0
10-Brom-5-carbamoyl-5H-dibenzazepin

Guidance literature:: Multi-step reaction with 2 steps

1: 2,2'-azobis(isobutyronitrile); sodium hydroxide; N-Bromosuccinimide / chlorobenzene / 12 h / 80 °C

2: ammonia / ethanol / 8 h / 40 - 60 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); ammonia; sodium hydroxide; In ethanol; chlorobenzene;