(R)-(-)-14-Methyl-8-hexadecyn-1-ol

Base Information

Chemical Name:(R)-(-)-14-Methyl-8-hexadecyn-1-ol
CAS No.:64566-18-3
Molecular Formula:C17H32O
Molecular Weight:252.44
Hs Code.:
DSSTox Substance ID:DTXSID601016004
Nikkaji Number:J596.621C

Synonyms:(R)-(-)-14-Methyl-8-hexadecyn-1-ol;64566-18-3;14-Methyl-8-hexadecyn-1-ol #;GGNPJEDYBWMUJF-QGZVFWFLSA-N;DTXSID601016004;[R,(?)]-14-Methyl-8-hexadecyne-1-ol

Suppliers and Price of (R)-(-)-14-Methyl-8-hexadecyn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (R)-(-)-14-Methyl-8-hexadecyn-1-ol

Chemical Property:

XLogP3:6.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:11
Exact Mass:252.245315640
Heavy Atom Count:18
Complexity:220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)CCCCC#CCCCCCCCO
Isomeric SMILES:CC[C@@H](C)CCCCC#CCCCCCCCO

Technology Process of (R)-(-)-14-Methyl-8-hexadecyn-1-ol

There total 2 articles about (R)-(-)-14-Methyl-8-hexadecyn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 821-57-8
7-chloroheptanoic acid

: 64566-18-3
14-methyl-8-hexadecyn-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / tetrahydrofuran; hexamethylphosphoric acid triamide / 1) 20 deg C, 12 h, 2) 40 deg C, 5 h

2: 81 percent / LiAlH₄ / diethyl ether / 1 h / Heating

3: 62 percent / 1) LiNH₂ / 1) liq. NH₃ - THF, -40 deg C, 2) THF - HMPT, 40 deg C, 3 h

With lithium aluminium tetrahydride; lithium amide; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether;

Reference yield:

: 10422-35-2,99032-67-4,534-00-9,5973-11-5
1-bromo-2-methyl-butane

: 64566-18-3
14-methyl-8-hexadecyn-1-ol

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) Mg / 1.) ether, 2.) ether, reflux, 16 h

2: 1.) NaBH₄, BF₃-etherate, 2.) 3 N aq. NaOH, 3.) 30percent aq. H₂O₂ / 1.) THF, 20-25 deg C, 20-25 min, 3.) THF, 30-35 deg C, 2 h

3: 76 percent / phosphorus tribromide / 20 h / 55 - 60 °C

4: 66 percent / liquid ammonia / 6 h

5: 1.) lithium amide, hexamethylphosphorotriamide / 1.) 20 deg C, 1 h, 2.) 40-45 deg C, 10 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; sodium tetrahydroborate; lithium amide; boron trifluoride diethyl etherate; dihydrogen peroxide; phosphorus tribromide; magnesium; In ammonia;

Reference yield:

: 64566-18-3
14-methyl-8-hexadecyn-1-ol

: 60609-53-2,60609-52-1
(Z)-14-Methyl-8-Hexadecenal

Guidance literature:: Multi-step reaction with 2 steps

1: sodium borohydride, ethylenediamine / nickel acetate / aq. ethanol

2: pyridinium chlorochromate / CH₂Cl₂ / 7 h

With sodium tetrahydroborate; ethylenediamine; pyridinium chlorochromate; nickel diacetate; In ethanol; dichloromethane;