4-[(4-Methylphenyl)sulfanyl]quinazoline

Base Information

Chemical Name:4-[(4-Methylphenyl)sulfanyl]quinazoline
CAS No.:3458-44-4
Molecular Formula:C15H12N2S
Molecular Weight:252.34
Hs Code.:
NSC Number:65067
DSSTox Substance ID:DTXSID10289884
Nikkaji Number:J3.321.211I
Wikidata:Q82027407
Mol file:3458-44-4.mol

Synonyms:4-[(4-methylphenyl)sulfanyl]quinazoline;3458-44-4;4-(p-Tolylthio)quinazoline;NSC65067;NCIOpen2_003046;SCHEMBL6213388;DTXSID10289884;NSC-65067;AKOS001364613;CCG-288671;Z62455185

Suppliers and Price of 4-[(4-Methylphenyl)sulfanyl]quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-[(4-Methylphenyl)sulfanyl]quinazoline

Chemical Property:

Vapor Pressure:3.32E-07mmHg at 25°C
Boiling Point:430.2°Cat760mmHg
Flash Point:214°C
Density:1.26g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:252.07211956
Heavy Atom Count:18
Complexity:263

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)SC2=NC=NC3=CC=CC=C32

Technology Process of 4-[(4-Methylphenyl)sulfanyl]quinazoline

There total 4 articles about 4-[(4-Methylphenyl)sulfanyl]quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: 3458-44-4
4-p-tolylsulfanyl-quinazoline

Guidance literature:

Reference yield:

: 10371-42-3
S-(4-methylphenyl) thiobenzoate

: 92104-25-1
4-(4-chlorophenoxy)quinazoline

: 2005-08-5
4-chlorophenyl benzoate

: 3458-44-4
4-p-tolylsulfanyl-quinazoline

Guidance literature:: With hydridotetakis(triphenylphosphine)rhodium(I); o-phenylenebis(diphenylphosphine); In chlorobenzene; for 5h; Inert atmosphere; Reflux;
DOI:10.1021/acs.joc.6b02585

Reference yield:

: 491-36-1
4-Hydroxyquinazoline

: 3458-44-4
4-p-tolylsulfanyl-quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 1 h / 20 °C / Inert atmosphere

2: acetonitrile / 23 h / 45 °C / Inert atmosphere

With N-ethyl-N,N-diisopropylamine; In acetonitrile;
DOI:10.3390/molecules18055580