1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-

Base Information

Chemical Name:1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-
CAS No.:646995-81-5
Molecular Formula:C13H16O2
Molecular Weight:204.26500
Hs Code.:
DSSTox Substance ID:DTXSID50477288
Wikidata:Q82309686

Synonyms:646995-81-5;1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-;DTXSID50477288

Suppliers and Price of 1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-

Chemical Property:

PSA：18.46000
LogP:3.06520
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:204.115029749
Heavy Atom Count:15
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(OC(C(O1)C2=CC=CC=C2)C=C)C
Isomeric SMILES:CC1(O[C@@H]([C@@H](O1)C2=CC=CC=C2)C=C)C

Technology Process of 1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)-

There total 2 articles about 1,3-Dioxolane, 4-ethenyl-2,2-dimethyl-5-phenyl-, (4R,5S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 135414-96-9
(1S,2R)-1-phenylbut-3-ene-1,2-diol

: 77-76-9
2,2-dimethoxy-propane

: 646995-81-5
(4S,5R)-2,2-dimethyl-4-phenyl-5-ethenyl[1,3]dioxolane

Guidance literature:: With Amberlyst(R)-15H; In dichloromethane; at 20 ℃;
DOI:10.1016/j.tetasy.2003.10.026

Reference yield:

: 675834-56-7
(1S,2R)-1-phenyl-1-(tert-butyldimethylsilyloxy)but-3-en-2-ol

: 646995-81-5
(4S,5R)-2,2-dimethyl-4-phenyl-5-ethenyl[1,3]dioxolane

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / tetrabutylammonium fluoride / tetrahydrofuran / 2 h / 20 °C

2: 99 percent / Amberlyst(R)-15H / CH₂Cl₂ / 20 °C

With Amberlyst(R)-15H; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetasy.2003.10.026

Reference yield: 68.0%

: 646995-81-5
(4S,5R)-2,2-dimethyl-4-phenyl-5-ethenyl[1,3]dioxolane

: 155749-26-1
[(4R,5S)-2,2-dimethyl-5-phenyl[1,3]dioxolan-4-yl]methanol

Guidance literature:: (4S,5R)-2,2-dimethyl-4-phenyl-5-ethenyl[1,3]dioxolane; With ozone; In dichloromethane; at -78 - 20 ℃;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1016/j.tetasy.2003.10.026