Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester

Base Information

Chemical Name:Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester
CAS No.:646996-79-4
Molecular Formula:C19H15N5O2
Molecular Weight:345.36
Hs Code.:
DSSTox Substance ID:DTXSID90475960
Wikidata:Q82306800

Synonyms:646996-79-4;Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester;DTXSID90475960

Suppliers and Price of Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:345.12257474
Heavy Atom Count:26
Complexity:479

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=NN2C1=NN=N2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester

There total 1 articles about Tetrazolo[1,5-b]pyridazine-8-carboxylic acid, 6,7-diphenyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 54108-27-9
ethyl 3-chloro-5,6-diphenylpyridazine-4-carboxylate

: 646996-79-4
ethyl 6,7-diphenyltetrazolo[1,5-b]pyridazine-8-carboxylate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.3987/COM-03-9749

Reference yield: 91.0%

: 646996-79-4
ethyl 6,7-diphenyltetrazolo[1,5-b]pyridazine-8-carboxylate

: 646996-80-7
6,7-diphenyltetrazolo[1,5-b]pyridazine-8-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 6h; Heating;
DOI:10.3987/COM-03-9749

Reference yield:

: 646996-79-4
ethyl 6,7-diphenyltetrazolo[1,5-b]pyridazine-8-carboxylate

: [5-(6,7-diphenyl-tetrazolo[1,5-b]pyridazin-8-yl)-[1,3,4]oxadiazol-2-ylsulfanyl]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / hydrazine hydrate / ethanol / 6 h / Heating

2: 64 percent / potassium hydroxide; water / ethanol / 6 h / Heating

3: K₂CO₃ / acetone / 15 h / Heating

With potassium hydroxide; water; potassium carbonate; hydrazine hydrate; In ethanol; acetone;
DOI:10.3987/COM-03-9749