3-Pentylcyclobutanecarboxylic acid

Base Information

• Chemical Name: 3-Pentylcyclobutanecarboxylic acid
• CAS No.: 66016-19-1
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.252
• Hs Code.: 2916209090
• Mol file: 66016-19-1.mol

Synonyms:3-n-pentylcyclobutane-1-carboxylic acid;3-n-Pentyl-cyclobutan-1-carbonsaeure;CYCLOBUTANECARBOXYLIC ACID,3-PENTYL;3-Pentylcyclobutanecarboxylic acid;

Chemical Property of 3-Pentylcyclobutanecarboxylic acid

Chemical Property:

• Vapor Pressure: 0.00251mmHg at 25°C
• Boiling Point: 266.3°Cat760mmHg
• PKA: 4.83±0.40(Predicted)
• Flash Point: 127.9°C
• PSA: 37.30000
• Density: 0.999g/cm³
• LogP: 2.67750

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pentylcyclobutanecarboxylic acid

There total 10 articles about 3-Pentylcyclobutanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

3-Pentyl-cyclobutane-1,1-dicarboxylic acid diethyl ester (66016-04-4) → 3-n-pentylcyclobutane-1-carboxylic acid (66016-19-1)

Guidance literature:

diethyl 3-pentylcyclobutane-1,1-dicarboxylate; With water; potassium hydroxide; In ethanol; for 3h; Reflux;

With pyridine; for 18h; Reflux;

Reference yield:

p-propylphenyl 3-pentylcyclobutanecarboxylate + sodium carbonate (497-19-8) → 3-n-pentylcyclobutane-1-carboxylic acid (66016-19-1)

Guidance literature:

With sodium hydroxide; In ethanol;

Reference yield:

p-propylphenyl 3-pentylcyclobutanecarboxylate → 3-n-pentylcyclobutane-1-carboxylic acid (66016-19-1)

Guidance literature:

upstream raw materials:

diethyl n-pentylmalonate

diethyl malonate

3-Pentyl-cyclobutane-1,1-dicarboxylic acid diethyl ester

2-pentylpropane-1,3-diol

Downstream raw materials:

Toluene-4-sulfonic acid 3-pentyl-cyclobutylmethyl ester

Refernces

• 1、 -. "Cyclobutanecarboxylic acid derivatives and liquid crystalline compositions containing them". . . Retrieved 2008/06/13.
• 2、 Chain, L. K. M.,Gemmel, P. A.,Gray, G. W.,Lacey, D.,Toyne, K. J.. "Synthesis and liquid crystal properties of compounds incorporating cyclobutane, spiroheptane and dispirodecane rings". . p. 113 - 140. Retrieved 2007/10/02.