2-Phenazinecarbonitrile

Base Information

• Chemical Name: 2-Phenazinecarbonitrile
• CAS No.: 6479-93-2
• Molecular Formula: C13H7N3
• Molecular Weight: 205.21500
• Hs Code.: 2933990090
• Mol file: 6479-93-2.mol

Synonyms:2-Cyano-phenazin;2-Phenazinecarbonitrile;Phenazin-2-carbonitril;2-Cyanophenazine;

Chemical Property of 2-Phenazinecarbonitrile

Chemical Property:

• PSA: 49.57000
• LogP: 2.65468

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Phenazinecarbonitrile

There total 16 articles about 2-Phenazinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-(4-cyanophenyl)-1,3,2-benzodiazaborole (1435933-07-5) → phenazine-2-carbonitrile (6479-93-2)

Guidance literature:

With silver(l) oxide; In dimethyl sulfoxide; at 80 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1039/d1cc06705b

Reference yield: 65.0%

N-(3-cyanophenyl)-N-(2-nitrosophenyl)amine → 1-cyanophenazine (411211-73-9) + phenazine-2-carbonitrile (6479-93-2)

Guidance literature:

With N,O-bis-(trimethylsilyl)-acetamide; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1016/j.tet.2017.04.046

Reference yield: 63.0%

10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-8-carbonitrile (1621867-54-6) → phenazine-2-carbonitrile (6479-93-2)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In acetonitrile; at 90 ℃; for 0.5h; Reagent/catalyst;

DOI:10.1021/ol501766m

upstream raw materials:

10-methyl-5,10-dihydro-phenazine-2-carbonitrile

2-cyano-10-methyl-5-phenazyl

3-nitro-4-(phenylamino)benzonitrile

4-(2-amino-anilino)-3-nitro-benzonitrile

Downstream raw materials:

phenazine-2-carboxylic acid

Refernces

• 1、 Wróbel, Zbigniew,Plichta, Karolina,Kwast, Andrzej. "Reactivity and substituent effects in the cyclization of N-aryl-2-nitrosoanilines to phenazines". . p. 3147 - 3152. Retrieved 2017/05/08.
• 2、 Laha, Joydev K.,Tummalapalli, K.S. Satyanarayana,Gupta, Ankur. "Palladium-catalyzed domino double n-arylations (inter- and intramolecular) of 1,2-diamino(hetero)arenes with o,o-dihalo(hetero)arenes for the synthesis of phenazines and pyridoquinoxalines". . p. 8330 - 8335. Retrieved 2014/01/06.