cis-3-Methylquinolizidine

Base Information

• Chemical Name: cis-3-Methylquinolizidine
• CAS No.: 6480-42-8
• Molecular Formula: C10H19N
• DSSTox Substance ID: DTXSID60477335
• Wikidata: Q82309773
• Mol file: 6480-42-8.mol

Synonyms:cis-3-methylquinolizidine;CTK2A2912;6480-42-8;DTXSID60477335

Chemical Property of cis-3-Methylquinolizidine

Chemical Property:

• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 153.151749610
• Heavy Atom Count: 11
• Complexity: 133

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1CCC2CCCCN2C1
• Isomeric SMILES: C[C@@H]1CC[C@H]2CCCCN2C1

Technology Process of cis-3-Methylquinolizidine

There total 11 articles about cis-3-Methylquinolizidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ trans-4-methylquinolizidine (4939-36-0,5591-01-5,6480-42-8)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 260 ℃; under 220652 Torr; Hydrogenation;

DOI:10.1021/ja01607a064

Reference yield:

2-hydroxymethyl-4-(2-pyridyl)-1-butanol (408332-74-1) → trans-4-methylquinolizidine (4939-36-0,5591-01-5,6480-42-8) + cis-4-methylquinolizidine (4939-36-0,5591-01-5,6480-42-8)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 260 ℃; under 220652 Torr; Hydrogenation;

DOI:10.1021/ja01607a064

Reference yield:

2-hydroxymethyl-4-(2-pyridyl)-1-butanol (408332-74-1) → trans-4-methylquinolizidine (4939-36-0,5591-01-5,6480-42-8) + cis-4-methylquinolizidine (4939-36-0,5591-01-5,6480-42-8)

Guidance literature:

With 1,4-dioxane; copper oxide-chromium oxide; at 260 ℃; under 220652 Torr; Hydrogenation;

DOI:10.1021/ja01607a064

upstream raw materials:

2-hydroxymethyl-4-(2-pyridyl)-1-butanol

6-methyl-2,3,4,5-tetrahydro-pyridine