4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine

Base Information

Chemical Name:4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine
CAS No.:64820-40-2
Molecular Formula:C22H19NOS
Molecular Weight:345.45700
Hs Code.:
DSSTox Substance ID:DTXSID50369533
Nikkaji Number:J1.567.073H
Mol file:64820-40-2.mol

Synonyms:4-(4-methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine;64820-40-2;HMS1530A22;Maybridge4_003190;DTXSID50369533;NCGC00176112-01;AJ-091/33281008;BRD-A96315807-001-01-7;2,3-Dihydro-4-(4-methoxyphenyl)-2-phenyl-1,5-benzothiazepine

Suppliers and Price of 4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine

Chemical Property:

PSA：46.89000
LogP:5.48870
XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:345.11873540
Heavy Atom Count:25
Complexity:451

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC3=CC=CC=C3SC(C2)C4=CC=CC=C4

Technology Process of 4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine

There total 8 articles about 4-(4-Methoxyphenyl)-2-phenyl-2,3-dihydro-1,5-benzothiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 22966-19-4
trans-4'-methoxychalcone

: 137-07-5
2-amino-benzenethiol

: 64820-40-2
2,3-dihydro-4-(4-methoxyphenyl)-2-phenyl-1,5-benzothiazepine

Guidance literature:: magnesium(II) perchlorate; In 1,2-dichloro-ethane; for 1h; Heating;
DOI:10.1055/s-2007-965892

Reference yield: 84.0%

: 137-07-5
2-amino-benzenethiol

: 959-23-9
4'-methoxychalcone

: 64820-40-2
2,3-dihydro-4-(4-methoxyphenyl)-2-phenyl-1,5-benzothiazepine

Guidance literature:: With tetra-N-butylammonium tribromide; In water; at 80 ℃; for 8h;
DOI:10.1080/10426507.2011.627900

Reference yield:

: 40358-31-4
2,3-dihydro-2,4-diphenyl-1,5-benzothiazepine

: 64820-40-2
2,3-dihydro-4-(4-methoxyphenyl)-2-phenyl-1,5-benzothiazepine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 48 h / Ambient temperature

2: 67 percent / triethylamine / Heating

With triethylamine; In methanol;
DOI:10.1007/BF00842834