2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine

Base Information

• Chemical Name: 2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine
• CAS No.: 64826-48-8
• Molecular Formula: C11H8ClNOS2
• Molecular Weight: 269.776
• DSSTox Substance ID: DTXSID60565887
• Wikidata: Q82451212
• Mol file: 64826-48-8.mol

Synonyms:64826-48-8;SCHEMBL11746620;2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine;DTXSID60565887

Chemical Property of 2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 268.9735839
• Heavy Atom Count: 16
• Complexity: 212

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=[N+](C(=C1)SSC2=CC=C(C=C2)Cl)[O-]

Technology Process of 2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine

There total 10 articles about 2-[(4-Chlorophenyl)disulfanyl]-1-oxo-1lambda~5~-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N,N-Diethyl-p-chlorbenzolsulfenamid (24398-21-8) + Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester (105398-69-4) → 4-chlorophenyl 1-oxo-pyridin-2-yl disulfide (64826-48-8) + N,N-diethylcyclohexanecarboxamide (5461-52-9)

Guidance literature:

In dichloromethane; for 24h; Ambient temperature;

DOI:10.1016/0040-4020(96)00487-5

Reference yield: 90.0%

N,N-Diethyl-p-chlorbenzolsulfenamid (24398-21-8) + 1-(adamantane-1-carbonyloxy)pyridine-2(1H)-thione (91233-19-1) → 4-chlorophenyl 1-oxo-pyridin-2-yl disulfide (64826-48-8) + (3r,5r,7r)-N,N-diethyladamantane-1-carboxamide (1501-90-2)

Guidance literature:

In dichloromethane; for 168h; Ambient temperature;

DOI:10.1016/0040-4020(96)00487-5 DOI:10.1080/10426509708545507

Reference yield: 89.0%

N,N-diisopropyl-S-4-chlorobenzenesulfenamide (71855-61-3) + 3-Phenyl-propionic acid 2-thioxo-2H-pyridin-1-yl ester (114050-31-6) → 4-chlorophenyl 1-oxo-pyridin-2-yl disulfide (64826-48-8) + N,N-diisopropyl-3-phenylpropionamide (20308-62-7)

Guidance literature:

for 120h; Ambient temperature;

DOI:10.1016/0040-4020(96)00487-5

upstream raw materials:

4,4'-dichlorodiphenyl disulfide

2,2'-dipyridyl disulfide bis-N-oxide

N,N-Diethyl-p-chlorbenzolsulfenamid

Cyclohexanecarboxylic acid 2-thioxo-2H-pyridin-1-yl ester