2,6-dichloro-5-nitro-pyrimidin-4-amine

Base Information

• Chemical Name: 2,6-dichloro-5-nitro-pyrimidin-4-amine
• CAS No.: 31221-68-8
• Molecular Formula: C4H2 Cl2 N4 O2
• Molecular Weight: 208.991
• Hs Code.: 2933599090
• Mol file: 31221-68-8.mol

Synonyms:Pyrimidine,4-amino-2,6-dichloro-5-nitro- (8CI); 2,6-Dichloro-4-amino-5-nitropyrimidine;4-Amino-2,6-dichloro-5-nitropyrimidine; 6-Amino-2,4-dichloro-5-nitropyrimidine;NSC 515794

Chemical Property of 2,6-dichloro-5-nitro-pyrimidin-4-amine

Chemical Property:

• Vapor Pressure: 2.37E-07mmHg at 25°C
• Melting Point: 160-162 °C
• Boiling Point: 422.7°Cat760mmHg
• PKA: -3.14±0.10(Predicted)
• Flash Point: 209.4°C
• PSA: 97.62000
• Density: 1.834g/cm³
• LogP: 2.37820
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dichloro-5-nitropyrimidin-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,6-Dichloro-5-nitropyrimidin-4-amine can be used effectively against powdery mildews.

Technology Process of 2,6-dichloro-5-nitro-pyrimidin-4-amine

There total 3 articles about 2,6-dichloro-5-nitro-pyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.7%

6-amino-5-nitro-1H-pyrimidine-2,4-dione (3346-22-3) → 2,6-dichloro-5-nitropyrimidin-4-amine (31221-68-8)

Guidance literature:

With trichlorophosphate; at 120 ℃; for 4.7h;

Reference yield: 37.0%

6-amino-2-methylthio-5-nitropyrimidin-4-ol (127726-91-4) → 2,6-dichloro-5-nitropyrimidin-4-amine (31221-68-8) + 6-chloro-2-(methylsulfanyl)-5-nitropyrimidin-4-amine (38136-96-8)

Guidance literature:

With N,N-diethylaniline; trichlorophosphate; for 2h; Heating;

Reference yield:

6-amino-5-nitro-1H-pyrimidine-2,4-dione (3346-22-3) + N,N-dimethyl-aniline (121-69-7,77733-26-7) → 2,6-dichloro-5-nitropyrimidin-4-amine (31221-68-8)

Guidance literature:

With trichlorophosphate;

DOI:10.1002/hlca.19510340311

upstream raw materials:

6-amino-5-nitro-1H-pyrimidine-2,4-dione

N,N-dimethyl-aniline

6-amino-2-methylthio-5-nitropyrimidin-4-ol

6-amino-5-nitro-1H-pyrimidine-2,4-dione

Downstream raw materials:

6-amino-2,4-dimethoxy-5-nitropyrimidine

2,4-dimercapto-5,6-diaminopyrimidine

4,5-diamino-2,6-dichloropyrimidine

2-chloro-5-nitropyrimidine-4,6-diamine