(4-Chloro-2-trifluoromethyl-phenyl)-thiourea

Base Information

Chemical Name:(4-Chloro-2-trifluoromethyl-phenyl)-thiourea
CAS No.:648415-77-4
Molecular Formula:C₈H₆ClF₃N₂S
Molecular Weight:254.663
Hs Code.:
DSSTox Substance ID:DTXSID40406320
Wikidata:Q82211232
Mol file:648415-77-4.mol

Synonyms:648415-77-4;(4-Chloro-2-trifluoromethyl-phenyl)-thiourea;[4-chloro-2-(trifluoromethyl)phenyl]thiourea;1-(4-Chloro-2-(trifluoromethyl)phenyl)thiourea;ST50158602;DTXSID40406320;AKOS002216063;CS-0331489;G11330

Suppliers and Price of (4-Chloro-2-trifluoromethyl-phenyl)-thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Chloro-2-trifluoromethylphenyl)thiourea
50mg
$ 45.00

Crysdot
1-(4-Chloro-2-(trifluoromethyl)phenyl)thiourea 97%
5g
$ 480.00

Chemcia Scientific
(4-Chloro-2-trifluoromethyl-phenyl)-thiourea ＞98%
2 G
$ 150.00

Total 2 raw suppliers

Chemical Property of (4-Chloro-2-trifluoromethyl-phenyl)-thiourea

Chemical Property:

PSA：74.68000
LogP:3.80800
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:253.9892316
Heavy Atom Count:15
Complexity:247

Purity/Quality:

99% ^*data from raw suppliers

(4-Chloro-2-trifluoromethylphenyl)thiourea ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)C(F)(F)F)NC(=S)N

Technology Process of (4-Chloro-2-trifluoromethyl-phenyl)-thiourea

There total 1 articles about (4-Chloro-2-trifluoromethyl-phenyl)-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1147550-11-5
ammonium thiocyanate

: 4-chloro-2-trifluoromethylaniline hydrochloric acid salt

: 648415-77-4
N-(4-chloro-2-trifluoromethylphenyl)thiourea

Guidance literature:: In water; for 4h; Heating;
DOI:10.1016/S0022-1139(03)00092-7

Reference yield:

: 648415-77-4
N-(4-chloro-2-trifluoromethylphenyl)thiourea

: 648415-79-6
2-amino-5-chloro-3-(trifluoromethyl)benzenethiol

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / CHCl₃ / 4 h / Heating

2: 53 percent / KOH / H₂O / Heating

With potassium hydroxide; bromine; In chloroform; water;
DOI:10.1016/j.bmc.2006.04.009

Reference yield:

: 648415-77-4
N-(4-chloro-2-trifluoromethylphenyl)thiourea

: 2-(4-methylbenzoyl)-7-chloro-3-methyl-5-trifluoromethyl-4H-1,4-benzothiazine

Guidance literature:: Multi-step reaction with 3 steps

1: bromine / CHCl₃ / 4 h / Heating

2: 53 percent / KOH / H₂O / Heating

3: 74.76 percent / dimethylsulfoxide / Heating

With potassium hydroxide; bromine; In chloroform; water; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2006.04.009