Tetradecanediimidamide, N,N''-bis(benzoyloxy)-

Base Information

• Chemical Name: Tetradecanediimidamide, N,N''-bis(benzoyloxy)-
• CAS No.: 648440-48-6
• Molecular Formula: C28H38N4O4
• Molecular Weight: 494.634
• Mol file: 648440-48-6.mol

Synonyms:

Chemical Property of Tetradecanediimidamide, N,N''-bis(benzoyloxy)-

Chemical Property:

• PSA: 126.86000
• LogP: 7.32660

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetradecanediimidamide, N,N''-bis(benzoyloxy)-

There total 4 articles about Tetradecanediimidamide, N,N''-bis(benzoyloxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1,12-bis-(N,N-hydroxyamidinyl)dodecane (648440-39-5) + benzoyl chloride (98-88-4) → 1,12-bis-(N,N'-benzoyloxyamidinyl)dodecane (648440-48-6)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

Reference yield: 87.0%

benzoyl chloride (98-88-4) → 1,12-bis-(N,N'-benzoyloxyamidinyl)dodecane (648440-48-6)

Guidance literature:

With triethylamine; In chloroform; at 5 - 25 ℃;

DOI:10.1016/j.bmcl.2008.12.058

Reference yield:

Tetradecandisaeuredinitril (7735-44-6) → 1,12-bis-(N,N'-benzoyloxyamidinyl)dodecane (648440-48-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / water / 72.25 h / Heating / reflux

2: triethylamine / N,N-dimethyl-formamide / 3 h / 20 °C

With hydroxylamine hydrochloride; triethylamine; In water; N,N-dimethyl-formamide;

upstream raw materials:

1,12-bis-(N,N-hydroxyamidinyl)dodecane

benzoyl chloride

1,12-dibromododecane

Tetradecandisaeuredinitril

Downstream raw materials:

1,12-bis[(5-phenyl-1,2,4-oxadiazole)-3-yl]dodecane

Refernces

• 1、 -. "Compounds with antiparasitic activity and medicines containing same". Page/Page column 12-13. . Retrieved 2008/06/13.