3-(4-Chlorophenyl)-7-hydroxychromen-2-one

Base Information

Chemical Name:3-(4-Chlorophenyl)-7-hydroxychromen-2-one
CAS No.:20050-82-2
Molecular Formula:C7H5N3OS
Molecular Weight:272.688
Hs Code.:
DSSTox Substance ID:DTXSID201228790
Pharos Ligand ID:XCSX8448VSLH
Metabolomics Workbench ID:74147
ChEMBL ID:CHEMBL3739747

Synonyms:3-(4-chlorophenyl)-7-hydroxy-2H-chromen-2-one;20050-82-2;3-(4-chlorophenyl)-7-hydroxychromen-2-one;CHEMBL3739747;SCHEMBL7124793;QIMAXWFBDUTNFD-UHFFFAOYSA-N;DTXSID201228790;BDBM50553873;STK788089;3(4'-Chlorophenyl)-7-hydroxycoumarin;AKOS000270917;CS-0253955;EN300-36449;VU0489615-1;SR-01000017905;SR-01000017905-1;3-(4-Chlorophenyl)-7-hydroxy-2H-1-benzopyran-2-one;F1862-0580

Suppliers and Price of 3-(4-Chlorophenyl)-7-hydroxychromen-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)-7-hydroxychromen-2-one

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:272.0240218
Heavy Atom Count:19
Complexity:385

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CC3=C(C=C(C=C3)O)OC2=O)Cl

Technology Process of 3-(4-Chlorophenyl)-7-hydroxychromen-2-one

There total 10 articles about 3-(4-Chlorophenyl)-7-hydroxychromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 20050-81-1
3-(4-chlorophenyl)-7-acetoxychromen-2-one

: 20050-82-2
3-(4-chlorophenyl)-7-hydroxy-2H-chromen-2-one

Guidance literature:: With ethanol; sulfuric acid; Reflux;
DOI:10.1007/s10600-009-9261-x

Reference yield: 48.27%

: 25307-03-3
4-chlorophenylacetic acid sodium salt

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 20050-82-2
3-(4-chlorophenyl)-7-hydroxy-2H-chromen-2-one

Guidance literature:: 4-chlorophenylacetic acid sodium salt; 2,4-Dihydroxybenzaldehyde; With acetic anhydride; at 180 - 190 ℃; for 5h;

With hydrogenchloride; In ethanol; water; for 8h; Reflux;
DOI:10.1021/acs.jmedchem.6b00609