Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-

Base Information

Chemical Name:Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-
CAS No.:648956-83-6
Molecular Formula:C12H17FO2S
Molecular Weight:244.33
Hs Code.:
DSSTox Substance ID:DTXSID60476803
Wikidata:Q82308650

Synonyms:648956-83-6;Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-;DTXSID60476803

Suppliers and Price of Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:244.09332912
Heavy Atom Count:16
Complexity:180

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)OC)SCCCCF

Technology Process of Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy-

There total 1 articles about Benzene, 2-[(4-fluorobutyl)thio]-1,4-dimethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 462-72-6
4-bromo-1-fluorobutane

: 1483-27-8
2,5-dimethoxythiophenol

: 648956-83-6
2-[(4-Fluorobutyl)thio]-1,4-dimethoxybenzol

Guidance literature:: With potassium hydroxide; In methanol; for 1h; Heating;
DOI:10.1002/hlca.200390210

Reference yield: 84.0%

: 93-61-8
N-methyl-N-phenylformamide

: 648956-83-6
2-[(4-Fluorobutyl)thio]-1,4-dimethoxybenzol

: 648957-07-7
4-[(4-Fluorobutyl)thio]-2,5-dimethoxybenzaldehyd

Guidance literature:: N-methyl-N-phenylformamide; 2-[(4-Fluorobutyl)thio]-1,4-dimethoxybenzol; With trichlorophosphate; at 15 - 60 ℃;

With water; for 0.5h;
DOI:10.1002/hlca.200390210

Reference yield:

: 648956-83-6
2-[(4-Fluorobutyl)thio]-1,4-dimethoxybenzol

: 4-[(4-Fluorobutyl)thio]-2,5-dimethoxybenzolethanamin Hydrochlorid

Guidance literature:: Multi-step reaction with 3 steps

1.1: POCl₃ / 15 - 60 °C

1.2: 84 percent / H₂O / 0.5 h

2.1: 86 percent / BuNH₂; AcOH / 0.13 h / Heating

3.1: LiAlH₄; H₂SO₄ / tetrahydrofuran; H₂O / cooling

3.2: 85 percent / HCl / propan-2-ol; H₂O

With lithium aluminium tetrahydride; sulfuric acid; acetic acid; N-butylamine; trichlorophosphate; In tetrahydrofuran; water; 1.1: Vilsmeier-formylation;
DOI:10.1002/hlca.200390210