Technology Process of 4H-1-Benzopyran-4-one,
7-decyl-2-[3,5-dimethoxy-4-(phenylmethoxy)phenyl]-3-(phenylmethoxy)-
There total 8 articles about 4H-1-Benzopyran-4-one,
7-decyl-2-[3,5-dimethoxy-4-(phenylmethoxy)phenyl]-3-(phenylmethoxy)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-Decene;
With
9-borabicyclo[3.3.1]nonane dimer;
In
tetrahydrofuran;
at 20 ℃;
for 6h;
3-benzyloxy-7-iodo-2-(4-benzyloxy-3,5-dimethoxy-phenyl)-chromen-4-one;
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide;
In
tetrahydrofuran; water;
for 15h;
Heating;
DOI:10.1016/j.bmc.2004.02.031
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 97 percent / triethylamine; 4-(N,N-dimethylamino)pyridine / CH2Cl2 / 2 h
2.1: 69 percent / AlCl3 / chlorobenzene / 90 h / 140 °C
3.1: 74 percent / potassium hydroxide / ethanol / 46 h
4.1: 96 percent / H2O2; NaOH / methanol; H2O / 24 h / 0 °C
5.1: 99 percent / potassium carbonate; potassium iodide / acetone / 19 h / Heating
6.1: 9-BBN / tetrahydrofuran / 6 h / 20 °C
6.2: 59 percent / PdCl2(dppf); NaOH / tetrahydrofuran; H2O / 15 h / Heating
With
dmap; potassium hydroxide; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; aluminium trichloride; dihydrogen peroxide; potassium carbonate; triethylamine; potassium iodide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; water; chlorobenzene; acetone;
2.1: Fries rearrangement / 3.1: aldol condensation / 4.1: Algar-Flynn-Oyamada oxidation / 6.2: Suzuki cross-coupling;
DOI:10.1016/j.bmc.2004.02.031
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 74 percent / potassium hydroxide / ethanol / 46 h
2.1: 96 percent / H2O2; NaOH / methanol; H2O / 24 h / 0 °C
3.1: 99 percent / potassium carbonate; potassium iodide / acetone / 19 h / Heating
4.1: 9-BBN / tetrahydrofuran / 6 h / 20 °C
4.2: 59 percent / PdCl2(dppf); NaOH / tetrahydrofuran; H2O / 15 h / Heating
With
potassium hydroxide; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide; potassium carbonate; potassium iodide;
In
tetrahydrofuran; methanol; ethanol; water; acetone;
1.1: aldol condensation / 2.1: Algar-Flynn-Oyamada oxidation / 4.2: Suzuki cross-coupling;
DOI:10.1016/j.bmc.2004.02.031
