Technology Process of 4H-1-Benzopyran-4-one,
6-decyl-2-[3,5-dimethoxy-4-(phenylmethoxy)phenyl]-3-hydroxy-
There total 3 articles about 4H-1-Benzopyran-4-one,
6-decyl-2-[3,5-dimethoxy-4-(phenylmethoxy)phenyl]-3-hydroxy- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-Decene;
With
9-borabicyclo[3.3.1]nonane dimer;
In
tetrahydrofuran;
at 20 ℃;
for 8h;
3-hydroxy-6-iodo-2-(4-benzyloxy-3,5-dimethoxy-phenyl)-chromen-4-one;
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium hydroxide;
In
tetrahydrofuran; water;
for 15h;
Heating;
DOI:10.1016/j.bmc.2004.02.031
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 49 percent / potassium hydroxide / ethanol / 360 h
2.1: 49 percent / H2O2; NaOH / tetrahydrofuran; H2O / 47 h / cooling
3.1: 9-BBN / tetrahydrofuran / 8 h / 20 °C
3.2: 72 percent / PdCl2(dppf); NaOH / tetrahydrofuran; H2O / 15 h / Heating
With
potassium hydroxide; sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide;
In
tetrahydrofuran; ethanol; water;
1.1: aldol condensation / 2.1: Algar-Flynn-Oyamada oxidation / 3.2: Suzuki cross-coupling;
DOI:10.1016/j.bmc.2004.02.031
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 49 percent / H2O2; NaOH / tetrahydrofuran; H2O / 47 h / cooling
2.1: 9-BBN / tetrahydrofuran / 8 h / 20 °C
2.2: 72 percent / PdCl2(dppf); NaOH / tetrahydrofuran; H2O / 15 h / Heating
With
sodium hydroxide; 9-borabicyclo[3.3.1]nonane dimer; dihydrogen peroxide;
In
tetrahydrofuran; water;
1.1: Algar-Flynn-Oyamada oxidation / 2.2: Suzuki cross-coupling;
DOI:10.1016/j.bmc.2004.02.031
