4-(2-Chloroacetamido)butanoic acid

Base Information

Chemical Name:4-(2-Chloroacetamido)butanoic acid
CAS No.:649556-05-8
Molecular Formula:C₆H₁₀ClNO₃
Molecular Weight:179.603
Hs Code.:
European Community (EC) Number:828-506-4
DSSTox Substance ID:DTXSID10700867
Nikkaji Number:J1.972.556A
Wikidata:Q82632350

Synonyms:4-(2-Chloroacetamido)butanoic acid;649556-05-8;4-[(2-chloroacetyl)amino]butanoic acid;SCHEMBL23794425;DTXSID10700867;4-(Chloroacetylamino)butyric acid;4-(2-Chloroacetamido)butanoicacid;AKOS010501998;CS-0234532;EN300-142641

Suppliers and Price of 4-(2-Chloroacetamido)butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-chloroacetamido)butanoicacid
100mg
$ 285.00

Total 2 raw suppliers

Chemical Property of 4-(2-Chloroacetamido)butanoic acid

Chemical Property:

PSA：69.89000
LogP:1.04650
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:179.0349209
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

4-(2-chloroacetamido)butanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(=O)O)CNC(=O)CCl

Technology Process of 4-(2-Chloroacetamido)butanoic acid

There total 1 articles about 4-(2-Chloroacetamido)butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 79-04-9
chloroacetyl chloride

: 56-12-2
4-amino-n-butyric acid

: 649556-05-8
4-(2-chloroacetamido)butanoic acid

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 2.5h; Reflux; Inert atmosphere;
DOI:10.1039/c2ob25996f

Reference yield:

: 649556-05-8
4-(2-chloroacetamido)butanoic acid

: 1401355-46-1
S-phenyl 4-(2-azidoacetamido)butanethioate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium azide / N,N-dimethyl-formamide / 24 h / 80 °C / Inert atmosphere

2.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere

With 4-methyl-morpholine; sodium azide; isobutyl chloroformate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1039/c2ob25996f