2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Base Information

Chemical Name:2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole
CAS No.:64957-65-9
Molecular Formula:C₁₆H₂₃NO₂
Molecular Weight:261.364
Hs Code.:
DSSTox Substance ID:DTXSID10497467
Nikkaji Number:J2.008.033G
Wikidata:Q82347045

Synonyms:64957-65-9;DTXSID10497467;2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Suppliers and Price of 2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:261.172878976
Heavy Atom Count:19
Complexity:325

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC1=C(C(=CC=C1)OC)C2=NC(CO2)(C)C

Technology Process of 2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

There total 1 articles about 2-(2-Butyl-6-methoxyphenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 693-03-8
n-butyl magnesium bromide

: 64957-86-4
2-(2,6-dimethoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole

: 64957-65-9
2-(2-butyl-6-methoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole

Guidance literature:: for 24h; Heating;
DOI:10.1016/j.tetlet.2003.12.127

Reference yield: 72.0%

: 64957-65-9
2-(2-butyl-6-methoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole

: 358-23-6
trifluoromethylsulfonic anhydride

: 139287-32-4
2-Butyl-6-methoxy-benzoic acid 2-methyl-2-trifluoromethanesulfonylamino-propyl ester

: 139287-35-7
N-[1-(2-Butyl-6-methoxy-phenyl)-1-(2-methyl-allyloxy)-meth-(E)-ylidene]-C,C,C-trifluoro-methanesulfonamide

Guidance literature:: In dichloromethane; at 0 ℃; for 0.166667h;
DOI:10.1080/00397919208021074

Reference yield:

: 64957-65-9
2-(2-butyl-6-methoxy-phenyl)-4,4-dimethyl-4,5-dihydro-oxazole

: 72216-31-0
2-(methoxy)-6-(n-butyl)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent / CH₂Cl₂ / 0.25 h / 0 °C

2: 100 percent / diethyl ether / Ambient temperature

3: 100 percent / 2.0M KOH / dimethylsulfoxide / 4 h / 110 °C

With potassium hydroxide; In diethyl ether; dichloromethane; dimethyl sulfoxide;
DOI:10.1080/00397919208021074