O-(N-Methylamino)propiophenone

Base Information

Chemical Name:O-(N-Methylamino)propiophenone
CAS No.:65037-44-7
Molecular Formula:C10H13NO
Molecular Weight:163.219
Hs Code.:
UNII:KX3QW8F384
Nikkaji Number:J1.146.501C

Synonyms:O-(N-Methylamino)propiophenone;KX3QW8F384;UNII-KX3QW8F384;1-Propanone, 1-(2-(methylamino)phenyl)-;65037-44-7;SCHEMBL605325

Suppliers and Price of O-(N-Methylamino)propiophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(N-Methylamino)propiophenone

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:156

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)C1=CC=CC=C1NC

Technology Process of O-(N-Methylamino)propiophenone

There total 4 articles about O-(N-Methylamino)propiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 17583-40-3
2-methylaminobenzonitrile

: 925-90-6
ethylmagnesium bromide

: 65037-44-7
1-[2-(methylamino)phenyl]propan-1-one

Guidance literature:: In tetrahydrofuran; at 0 - 50 ℃;
DOI:10.1002/adsc.202000427

Reference yield: 52.0%

: 100-61-8
N-methylaniline

: 107-12-0
propiononitrile

: 65037-44-7
1-[2-(methylamino)phenyl]propan-1-one

Guidance literature:: N-methylaniline; With boron trichloride; In benzene; Cooling with ice;

propiononitrile; With aluminum (III) chloride; In benzene; Reflux;
DOI:10.1055/s-0031-1291146

Reference yield:

: 394-47-8
2-fluorobenzonitrile

: 65037-44-7
1-[2-(methylamino)phenyl]propan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile; water / 12 h / 90 °C

2: tetrahydrofuran / 6 h / 80 °C

In tetrahydrofuran; water; acetonitrile;
DOI:10.1021/jacs.9b12554