Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-

Base Information

Chemical Name:Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-
CAS No.:651021-66-8
Molecular Formula:C₁₅H₉Br₂NO
Molecular Weight:379.051
Hs Code.:
DSSTox Substance ID:DTXSID00456402

Synonyms:651021-66-8;5-(3-Bromophenyl)-3-(4-bromophenyl)isoxazole;Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-;DTXSID00456402

Suppliers and Price of Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:378.90304
Heavy Atom Count:19
Complexity:294

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Br)C2=CC(=NO2)C3=CC=C(C=C3)Br

Technology Process of Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)-

There total 4 articles about Isoxazole, 5-(3-bromophenyl)-3-(4-bromophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 919121-16-7
(E)-3-(3-bromophenyl)-1-(4-bromophenyl)prop-2-en-1-one

: 651021-66-8
3-(4-bromo-phenyl)-5-(3-bromo-phenyl)-isoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / Br₂ / CHCl₃ / 20 °C

2: hydroxylamine hydrochloride / ethanol / Heating

With hydroxylamine hydrochloride; bromine; In ethanol; chloroform;
DOI:10.1021/jm0612867

Reference yield:

: 3132-99-8
m-bromobenzoic aldehyde

: 651021-66-8
3-(4-bromo-phenyl)-5-(3-bromo-phenyl)-isoxazole

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / aq. NaOH / ethanol / 25 °C

2: 98 percent / Br₂ / CHCl₃ / 20 °C

3: hydroxylamine hydrochloride / ethanol / Heating

With sodium hydroxide; hydroxylamine hydrochloride; bromine; In ethanol; chloroform; 1: Claisen-Schmidt condensation;
DOI:10.1021/jm0612867

Reference yield:

: 99-90-1
para-bromoacetophenone

: 651021-66-8
3-(4-bromo-phenyl)-5-(3-bromo-phenyl)-isoxazole

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / aq. NaOH / ethanol / 25 °C

2: 98 percent / Br₂ / CHCl₃ / 20 °C

3: hydroxylamine hydrochloride / ethanol / Heating

With sodium hydroxide; hydroxylamine hydrochloride; bromine; In ethanol; chloroform; 1: Claisen-Schmidt condensation;
DOI:10.1021/jm0612867