N-Acetyl-L-phenylalanyl-L-leucinamide

Base Information

Chemical Name:N-Acetyl-L-phenylalanyl-L-leucinamide
CAS No.:65118-58-3
Molecular Formula:C17H25N3O3
Molecular Weight:319.404
Hs Code.:
DSSTox Substance ID:DTXSID10563191
Nikkaji Number:J861.689B
Wikidata:Q82447565

Synonyms:N-Acetyl-L-phenylalanyl-L-leucinamide;65118-58-3;SCHEMBL242142;DTXSID10563191

Suppliers and Price of N-Acetyl-L-phenylalanyl-L-leucinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of N-Acetyl-L-phenylalanyl-L-leucinamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:319.18959167
Heavy Atom Count:23
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C
Isomeric SMILES:CC(C)C[C@@H](C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C

Technology Process of N-Acetyl-L-phenylalanyl-L-leucinamide

There total 3 articles about N-Acetyl-L-phenylalanyl-L-leucinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH₂

: 2361-96-8
ethyl N-acetyl-(L)-phenylalaninate

: 65118-58-3
N-Ac-L-Phe-L-Leu-NH₂

Guidance literature:: With subtilisin-CLEC; In acetonitrile; at 40 ℃; for 29h;
DOI:10.1021/jo9618334

Reference yield: 83.0%

: 687-51-4,13079-20-4,13366-40-0,15893-47-7
H-L-Leu-NH₂

: 108395-58-0
acetyl L-phenylalanine chloroethyl ester

: 65118-58-3
N-Ac-L-Phe-L-Leu-NH₂

Guidance literature:: With porcine pancreatic lipase; In toluene; at 45 ℃; for 48h;
DOI:10.1021/ja00246a060

Reference yield:

: 3618-96-0
(S)-N-acetylphenylalanine

: 10466-61-2
(2S)-amino-4-methylpentanamide hydrochloride

: 65118-58-3
N-Ac-L-Phe-L-Leu-NH₂

Guidance literature:: With baker's yeast (Saccharomyces cerevisiae NCIM 3305) immobilized in calcium alginate beads suspended in reverse micellar medium of 0.1 M bis(2-ethylhexyl)sulphosuccinate sodium salt; glycine-NaOH buffer; In 2,2,4-trimethylpentane; Product distribution; Ambient temperature; other L-amino acid derivatives; effect of water content in micellar medium on peptide bond formation;
DOI:10.1039/c39900001548