4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-

Base Information

Chemical Name:4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-
CAS No.:86818-94-2
Molecular Formula:C28H26ClN3O4
Molecular Weight:503.9767
Hs Code.:
Wikidata:Q76389144

Synonyms:BRN 4608853;4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-;86818-94-2;C28H26ClN3O4;C28-H26-Cl-N3-O4;LS-79883

Suppliers and Price of 4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-

Chemical Property:

Vapor Pressure:2.1E-18mmHg at 25°C
Boiling Point:681.1°Cat760mmHg
Flash Point:365.7°C
Density:1.28g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:503.1611840
Heavy Atom Count:36
Complexity:814

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C=C2C(=O)N(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N5CCOCC5)OC
Isomeric SMILES:COC1=C(C=C(C=C1)/C=C\2/C(=O)N(C(=N2)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N5CCOCC5)OC

Technology Process of 4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)-

There total 6 articles about 4H-Imidazol-4-one, 3,5-dihydro-2-(4-chlorophenyl)-5-((3,4-dimethoxyphenyl)methylene)-3-(4-(4-morpholinyl)phenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2524-67-6,86759-37-7
4-morpholino-4-yl-phenylamine

: 86818-82-8
2-(4-Chloro-phenyl)-4-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-4H-oxazol-5-one

: 86818-94-2
2-(4-Chloro-phenyl)-5-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-3-(4-morpholin-4-yl-phenyl)-3,5-dihydro-imidazol-4-one

Guidance literature:: With zinc(II) chloride; In ethanol; at 170 ℃; for 0.5h; or with pyridine, 8h, reflux;

Reference yield: 60.0%

: 86818-84-0
α-(p-Chlorophenylcarboxamido)-β-(3,4-dimethoxyphenyl)acrylic acid p-morpholinophenylcarboxamide

: 86818-94-2
2-(4-Chloro-phenyl)-5-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-3-(4-morpholin-4-yl-phenyl)-3,5-dihydro-imidazol-4-one

Guidance literature:: Heating;

Reference yield:

: 13450-77-6
4-chlorohippuric acid

: 86818-94-2
2-(4-Chloro-phenyl)-5-[1-(3,4-dimethoxy-phenyl)-meth-(Z)-ylidene]-3-(4-morpholin-4-yl-phenyl)-3,5-dihydro-imidazol-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Ac₂O, NaOAc / 2 h / Heating

2: 80 percent / ZnCl₂ / ethanol / 0.5 h / 170 °C / or with pyridine, 8h, reflux

With sodium acetate; acetic anhydride; zinc(II) chloride; In ethanol;